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142. Cooling-evoked hemodynamic perturbations facilitate sympathetic activity with subsequent myogenic vascular oscillations via alpha2-adrenergic receptors
- Creator:
- Lin, Y.-H., Liu, Y.-P., Lin, Y.-C., Lee, P.-L., and Tung, C.-S.
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, cold stimulation, power spectral analysis, sympathetic activation, alpha2-adrenoceptors, myogenic vascular oscillations, 14, and 612
- Language:
- English
- Description:
- This study extends our previous work by examining the effects of alpha2 -adrenoceptors under cold stimulation involving the increase of myogenic vascular oscillations as increases of very-low-frequency and low-frequency of the blood pressure variab ility. Forty-eight adult male Sprague-Dawley rats were randomly divided into four groups: vehicle; yohimbine; hexamethonium+yohimbine; guanethidine+yohimbine. Systolic blood pressure, heart rate, power spectral analysis of spontaneous blood pressure and he art rate variability and spectral coherence at very-low-frequency (0.02 to 0.2 Hz), low-frequency (0.2 to 0.6 Hz), and high-frequency (0.6 to 3.0 Hz) regions were monitored using telemetry. Key findings are as follows: 1) Cooling-induced pressor response was attenuated by yohimbine and further attenuated by hexamethonium+yohimbine and guanethidine+yohimbine, 2) Cooling-induced tachycardia response of yohimbine was attenuated by hexame - thonium+yohimbine and guanethidine+yohimbine, 3) Different patterns of p ower spectrum reaction and coherence value compared hexamethonium+yohimbine and guanethi-dine+yohimbine to yohimbine alone under cold stimulation. The results suggest that sympathetic activation of the postsynaptic alpha2-adrenoceptors causes vasoconstriction and heightening myogenic vascular oscillations, in turn, may increase blood flow to prevent tissue damage under stressful cooling challenge., Y.-H. Lin, Y.-P. Liu, Y.-C. Lin, P.-L. Lee, C.-S. Tung., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
143. Costanera Sur - za zvířaty v argentinském velkoměstě
- Creator:
- Andrej Funk and Funková, Kateřina
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Zoologie, zoologie, národní parky, ptáci, savci, životní prostředí, ekologie, national parks, birds, mammals, environment, ecology, 2, and 59
- Language:
- Czech
- Description:
- The Costanera Sur ecological reserve in Buenos Aires, Argentina, was established in 1986 on the banks of the Rio de la Plata on excavated substrata landfill, where free space was left for plant and animal communities to take over. The 350 ha of the reserve include such biotopes as wetlands, pampas and small areas of woodland, providing a valuable site for the city's inhabitants to meet various species of animals in close proximity to the historical city centre, e.g. 270 bird species have been recorded there., Andrej Funk, Kateřina Funková., Ekologická rezervace Costanera Sur v Buenos Aires v Argentině vznikla v roce 1986 na břehu Río de La Plata na skládce vytěženého substrátu, kde byl ponechán volný prostor k sukcesi společenstev rostlin a živočichů. Na ploše 350 ha rezervace zahrnuje biotopy mokřadů, pampy a malých úseků lesa a představuje cennou lokalitu pro rekreaci obyvatel města i pro poznávání různých druhů zvířat v těsné blízkosti historického centra města. Zatím zde byl doložen výskyt např. 270 druhů ptáků., and cze
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
144. Cryoprotectant systems and cold tolerance of insects inhabiting central Yakutia (Russian Far East)
- Creator:
- Li, Natalia G.
- Format:
- print, počítač, and online zdroj
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Zoologie, glycerol, hmyz, insects, freeze-tolerance, ice nucleators, cold hardiness potential, Siberian insects, 2, and 59
- Language:
- English
- Description:
- Strong tolerance of freezing is an important strategy for insects living in extremely cold regions. They produce highly effective cryoprotectant systems consisting of ice-nucleating proteins and polyols, which enables tolerable freezing of the body fluid. Therefore, the measurement of the concentrations of polyols and the activity of ice nucleators in the haemolymph is an essential tool for describing tolerance to ice formation in insects occurring in particularly cold places. This study evaluates three parameters: insect body supercooling point (SCP), haemolymph glycerol content and the profile of haemolymph ice nucleating activity that characterize the strategies of cold adaptation and cold hardiness in two previously unstudied beetles, Chrysolina graminis graminis L. and Galerucella nymphaea L., inhabiting Yakutia (Russian Far East, latitude 62°N). The high SCP values, ice nucleating activity and survival of the chrysomelids after freezing indicate that both species are tolerant of freezing. According to the profiles of ice-nucleating activity, the haemolymph from C. graminis graminis is characterized by a higher nucleating potential than that from G. nymphaea. The glycerol level is also higher in C. graminis graminis. The results indicate that both species develop tolerance to low temperatures, but the cold hardiness potential of C. graminis graminis is greater than that of G. nymphaea. This was revealed by the survival test, in which beetles were frozen to a temperature of -22°C for 30 min; 86% of C. graminis graminis and 72% of G. nymphaea survived the test. Thus, the freeze-tolerance of these beetles seems to be based on the production of an integrated cryoprotectant system, the quality of which apparently influences the range of their cold resistance., Natalia G. Li., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
145. Čtvrtá studentská muzikologická konference
- Creator:
- Ledvinka, Martin
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Univerzita Karlova., Ústav hudební vědy, 2011-2020, hudební konference, muzikologie, vysoké školy, conferences on music, musicology, universities and colleges, Praha (Česko), Prague (Czechia), 78.01, 78:005.745, 378, and (046)
- Language:
- Czech
- Description:
- Příspěvek Martina Ledvinky je zprávou o muzikologické konferenci studentů Ústavu hudební vědy FF UK, která se uskutečnila v prostorách Kabinetu hudební historie EÚ AV ČR dne 24. května 2012., Martin Ledvinka., Rubrika: Konference, and Cizojazyčné resumé není.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
146. Čtvrtstoletí průzkumu vážek na Podblanicku
- Creator:
- Lubomír Hanel
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Zoologie, entomologie, vážky, entomology, Odonata, Podblanicko (Česko), Podblanicko (Czechia), 2, and 59
- Language:
- Czech
- Description:
- Lubomír Hanel.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
147. Cyclic AMP synchronizes evoked quantal release at frog neuromuscular junctions
- Creator:
- Bukcharaeva, E., Samigullin, D., Nikolsky, E. E., and František Vyskočil
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, acetylcholin, acetylcholine, frog muscle, quantal release, cAMP, 14, and 612
- Language:
- English
- Description:
- At frog neuromuscular junction, noradrenaline (NA) shortens the release period for evoked quantal release acting on a b 1 receptor. To test the hypothesis that this action of NA is mediated by cAMP, we measured the latencies of focally recorded uni-quantal endplate currents (EPCs) after application of dibutyryl-cAMP (db-cAMP) and adenylyl cyclase activator, forskolin. The interval between the time when responses with minimal delay appeared and the point at which 90 % of all latencies had occurred (P90 parameter) was shortened in the presence of both 1x10-6 mol/l db-cAMP and 1x10-6 mol/l forskolin by about 30 %. The cAMP-induced shortening is equal to that found after application of NA and effects of both drugs are not additive., E. Bukcharaeva, D. Samigullin, E. E. Nikolsky, F. Vyskočil., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
148. Cyclosporin a modifies cytoplasmic calcium levels in isolated hepatocytes exposed to oxidative stress due to tert-butyl hydroperoxide
- Creator:
- Eva Kmoníčková, Ludmila Kameníková, Sixtus Hynie, and Hassan Farghali
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, hypertenze, hypertension, rat hepatocytes, Ca2+i, cyclosporin A, 14, and 612
- Language:
- English
- Description:
- Within the framework of our studies on hypertension in various rat strains, we have examined the effect of cyclosporin A (CsA) on intracellular calcium signaling under conditions of oxidative stress. For these preliminary experiments, we have chosen isolated hepatocytes of normotensive rats as a model system for the study of the role of intracellular calcium. We used tert-butyl hydroperoxide (t-BHP, 1 mmol.l-1) as an prooxidant agent. When compared to the controls, we found increased levels of cytosolic free calcium concentration (Ca2+i) during 120 min incubation. The preincubation of hepatocytes with CsA in the concentration of 0.5 m mol.l-1 did not change the physiological level of cytosolic calcium. However, a dual action of CsA on elevated Ca2+i was observed during oxidative injury of hepatocytes: while in the first period of incubation CsA increased Ca2+i, CsA reduced the effect of t-BHP on Ca2+i during the next period of incubation. This indicates the ability of CsA to modify oxidative stress, but further studies are necessary to explain these findings., E. Kmoníčková, L. Kameníková, S. Hynie, H. Farghali., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
149. Cytokiny a biologická léčba
- Creator:
- Ilja Trebichavský
- Format:
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Biochemie. Molekulární biologie. Biofyzika, molekulární biologie, cytokiny, biologická léčba, molecular biology, cytokines, biologic therapy, 2, and 577
- Language:
- Czech
- Description:
- Cytokiny jsou proteiny, které regulují růst, diferenciaci a aktivaci buněk. Jejich účinek se široce využívá pro léčbu zánětlivých a nádorových onemocnění. Anti-cytokinová léčba je velmi slibná, ale přinese v blízké budoucnosti velké finanční zatížení zdravotnictví., Cytokines are proteins that regulate the growth, differentiation and activation of cells. Their functions are used in therapy of inflammatory diseases and cancer. Antibody blockade of cytokines seems to be very promising, but it will result in considerable financial burden for healthcare in future., and Ilja Trebichavský.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
150. CzechGlobe v Bruselu
- Creator:
- Šprtová, Hana
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Věda. Všeobecnosti. Základy vědy a kultury. Vědecká práce, Česká styčná kancelář pro výzkum a vývoj v Bruselu (projekt), 21. století, výzkum a vývoj, vědecké programy, globální změny, research and development, scientific programs, global changes, 12, and 00
- Language:
- Czech
- Description:
- Hana Šprtová.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public