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1. 5. Beethoven-Studienkolleg: Beethoven edieren. Einführung in die Editionstechnik

Creator:
Petra Kolátorová
Format:
print, bez média, and svazek
Type:
article, články, journal articles, model:article, and TEXT
Subject:
Beethoven, Ludwig van, 1770-1827, 2011-2020, hudební konference, muzikologie, conferences on music, musicology, Bonn (Německo), Bonn (Germany), 78.01, 78:005.745, and (046)
Language:
Czech
Description:
Příspěvek Petry Kolátorové je věnován mezinárodní muzikologické konferenci, která se uskutečnila v německém Bonnu ve dnech 27. až 29. srpna 2012., Petra Kolátorová., Rubrika: Konference, and Cizojazyčné resumé není.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. 7 věží: Karel IV. v hledáčku akademiků

Creator:
Marina Hužvárová
Format:
print, bez média, and svazek
Type:
article, biography, články, journal articles, model:article, and TEXT
Subject:
Historická věda. Pomocné vědy historické. Archivnictví, IV., český král a římský císař, Karel, 1316-1378, Akademie věd České republiky, historiografie, panovníci, interdisciplinární aspekty, historiography, kings and rulers, interdisciplinary aspects, Česko, Czechia, 8, and 930
Language:
Czech
Description:
The 700th birth anniversary of King of Bohemia and Holy Roman Emperor Charles IV has been designated as one of UNESCO´s important world anniversaries for 2016-2017. The Czech Academy of Sciences recreates the period of Charles IV at the exhibiton entitled Seven Towers. Charles IV through the eyes of academics (1316-2016) at the Science and Art Gallery. The visitors have an oppportunity to see the unique gold ducats with a picture of Charles IV. For this first time the most valuable archaeological discoveries of glass goblets are exhibited. Everyday items used by residents of the medieval city are also on display. The exhibition also shows a rare treasure of coins, which was hidden in the Emmaus monastery about 1370, as well as copies of the Constitutive Act of the Charles University, Charles´s Code Maiestas Carolina or late-medieval transcript of Charles´ Golden Bull. Personality of Charles IV is documented by commemorative coins, medals and seals bearing his image. Part of the exhibition is also a faithful copy of the statue of Charles IV from the Old Town Bridge Tower, the last sculptural portrait of the monarch before his death. and Marina Hužvárová.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

5. Acrylamide: a common food toxin related to physiological functions and health

Creator:
Semla, M., Goc, Z., Martiniaková, M., Omelka, R., and Formicki, G.
Format:
print, bez média, and svazek
Type:
article, články, journal articles, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, akrylamid, genotoxicita, oxidační stres, acrylamide, genotoxicity, oxidative stress, neurotoxicity, reproductive toxicity, 14, and 612
Language:
English
Description:
Acrylamide (AA) is a highly reactive organic compound capable of polymerization to form polyacrylamide, which is commonly used throughout a variety of industries. Given its toxic effect on humans and animals, the last 20 years have seen an increased interest in research devoted to the AA. One of the main sources of AA is food. AA appears in heated food following the reaction between amino acids and reduced sugars. Large concentrations of AA can be found in popular staples such as coffee, bread or potato products. An average daily consumption of AA is between 0.3-2.0 μg/kg b.w. Inhalation of acrylamide is related with occupational exposure. AA delivered with food is metabolized in the liver by cytochrome P450. AA biotransformation and elimination result in formation of toxic glycidamide (GA). Both, AA and GA can be involved in the coupling reaction with the reduced glutathione (GSH) forming glutathione conjugates which are excreted with urine. Biotransformation of AA leads to the disturbance in the redox balance. Numerous research proved that AA and GA have significant influence on physiological functions including signal propagation in peripheral nerves, enzymatic and hormonal regulation, functions of muscles, reproduction etc. In addition AA and GA show neurotoxic, genotoxic and cancerogenic properties. In 1994, International Agency for Research on Cancer (IARC) classified acrylamide as a potentially carcinogenic substance to human., M. Semla, Z. Goc, M. Martiniaková, R. Omelka, G. Formicki., and Obsahuje bibliografii
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

6. Adaptivní fylogeografie: od molekulárních markerů k funkčním genům

Creator:
Kotlík, Petr, Marková, Silvia, Filipi, Karolína, Strážnická, Michaela, and Searle, Jeremy B.
Format:
bez média and svazek
Type:
article, text, články, journal articles, model:article, and TEXT
Subject:
Biologické vědy, biologie, fylogeografie, adaptace živočichů, savci, genetika živočichů, animal adaptation, biology, phylogeography, mammals, animal genetics, Velká Británie, Great Britain, adaptivní fylogeografie, 2, and 57/59
Language:
Czech
Description:
Dlouhou dobu se předpokládalo, že populace obývající určitá území Evropy také tato území na konci doby ledové kolonizovaly jako první. Nové výzkumy však ukázaly, že v některých případech byla první příchozí populace později nahrazena jinou, pocházející z jiného glaciálního refugia. Náš článek ukazuje, že k takovému nahrazení jedné populace druhou došlo při kolonizaci Velké Británie norníkem rudým (Clethrionomys glareolus) a že při tom hrály roli fyziologické adaptace způsobené mutací v hemoglobinu., It has long been assumed that the populations that first colonized particular empty territory after the last ice age have remained there until the present day. However, recent findings in small mammals suggest that replacements involving a population from one glacial refugium at the cost of a population from another refugium may have been a not infrequent event. The article demonstrates that such population replacement took place during post-glacial colonization of Great Britain by the Bank Vole (Clethrionomys glareolus) and that physiological differences conferred by haemoglobin have probably played a role in this process., and Petr Kotlík, Silvia Marková, Karolína Filipi, Michaela Strážnická, Jeremy B. Searle.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

7. Adopce mláďat káně lesní v hnízdech orla mořského

Creator:
Ivan Literák and Mráz, Jakub
Format:
bez média and svazek
Type:
article, text, články, journal articles, model:article, and TEXT
Subject:
Biologické vědy, biologie, káně lesní, orel mořský, adopce, common buzzard, biology, white-tailed sea eagle, Evropa střední, Europe, Central, hnízdní adopce, 2, and 57/59
Language:
Czech
Description:
Ve střední Evropě (Česko, Maďarsko a Polsko) jsme zaznamenali 9 případů zajímavé adopce mláďat káně lesní (Buteo buteo) v hnízdech orlů mořských (Haliaeetus albicilla). Adoptovaná mláďata byla v dobré kondici, dospělí orli mořští se o ně starali a mláďata byla nakonec úspěšně vyvedena., Nine interesting cases of young Common Buzzards (Buteo buteo) adopted in nests of White-tailed Sea Eagle (Haliaeetus albicilla) in central Europe (Czech Republic, Poland and Hungary) are reviewed. The B. buteo nestlings adopted were in good condition, the adult H. albicilla fed and cared for them properly, and the young birds successfully fledged., and Ivan Literák, Jakub Mráz.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

8. Adult neurogenesis in the hippocampus from a perspective of discrimination and generalization: a hypothesis

Creator:
Pistikova, A., Brozka, H., and Aleš Stuchlík
Format:
print, bez média, and svazek
Type:
article, články, journal articles, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, diskriminace, fyziologie, discrimination, physiology, adult neurogenesis, function, generalization, spatial memory, pattern Separation, 14, and 612
Language:
English
Description:
The function of adult neurogenesis in the dentate gyrus is not yet completely understood, though many competing theories have attempted to explain the function of these newly -generated neurons. Most theories give adult neurogenesis a role in aiding known hippocampal/dentate gyrus functions. Other theories offer a novel role for these new cells based on their unique physiological qualities, such as their low excitability threshold. Many behavioral tests have been used to test these theories, but results have been inconsistent and often contradictory. Substantial variability in tests and protocols may be at least partially responsible for the mixed results. On the other hand, conflicting results arising from the same tests can serve as aids in elucidating the function of adult neurogenesis. Here, we offer a hypothesis that considers the cognitive nature of tasks commonly used to assess the function of adult neurogenesis, and introduce a dichotomy between tasks focused on discrimination vs. generalization. We view these two aspects as opposite ends of the continuous spectrum onto which traditional tests can be mapped. We propose that high neurogenesis favors behavioral discrimination while low adult neurogenesis favors behavioral generalization of a knowledge or rule. Since many tasks require both, the effects of neurogenesis could be cancelled out in many cases. Although speculative, we hope that our view presents an interesting and testable hypothesis of the effect of adult neurogenesis in traditional behavioral tasks. We conclude that new, carefully designed behavioral tests may be necessary to reach a final consensus on the role of adult neurogenesis in behavior., A. Pistikova, H. Brozka, A. Stuchlik., and Obsahuje bibliografii
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

9. Aerobic exercise of low to moderate intensity corrects unequal changes in BKCa subunit expression in the mesenteric arteries of spontaneously hypertensive rats

Creator:
Zhang, Y., Chen, Y., Zhang, L., Lu, N., and Shi, L.
Format:
print, bez média, and svazek
Type:
article, články, journal articles, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, hypertenze, hypertension, exercise intensity, BKCa channel, 14, and 612
Language:
English
Description:
Accumulating evidence indicates that hypertension is associated with "ion channel remodeling" of vascular smooth muscle cells (VSMCs). The objective of this study was to determine the effects of exercise intensity/volume on hypertension-associated changes in large-conductance Ca2+-activated K+ (BKCa) channels in mesenteric arteries (MAs) from spontaneously hypertensive rats (SHR). Male SHRs were randomly assigned to three groups: a low-intensity aerobic exercise group (SHR-L: 14 m/min), a moderate-intensity aerobic exercise group (SHR-M: 20 m/min), and a sedentary group (SHR). Age-matched Wistar-Kyoto rats (WKYs) were used as normotensive controls. Exercise groups completed an 8-week exercise program. Elevation of the α and β1 proteins was unequal in MA myocytes from SHRs, with the β1 subunit increasing more than the α subunit. BKCa contribution to vascular tone regulation was higher in the myocytes and arteries of SHRs compared to WKYs. SHR BKCa channel subunit protein expression, β1/α ratio, whole cell current density and single-channel open probability was also increased compared with WKYs. Aerobic exercise lowered systemic blood pressure and normalized hypertension-associated BKCa alterations to normotensive control levels in the SHRs. These effects were more pronounced in the moderate-intensity group than in the low-intensity group. There is a dose-effect for aerobic exercise training in the range of low to moderate-intensity and accompanying volume for the correction of the pathological adaptation of BKCa channels in myocytes of MAs from SHR., Y. Zhang, Y. Chen, L. Zhang, N. Lu, L. Shi., and Obsahuje bibliografii
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public