Šumava lakes have been recovering over the last 30 years from acidification caused by high atmospheric deposition of sulphur and nitrogen. Regeneration was manifested by decreasing acidity and increasing biodiversity (except for fish). It was temporarily interrupted by Spruce Bark Beetle (Ips typographus) infestation in lake catchments. Spruce defoliation and changes in light and humidity conditions caused enhanced mineralization of soil humus layer resulting in nitrate leaching and also partial acidification (only temporary, within a few decades the lakes will profit from the release of nitrogen from the ecosystem). and Jakub Hruška a kol.
Over a century ago, hyperplasia and hypertrophy of astrocytes was noted as a histopathological hallmark of multiple sclerosis and was hypothesized to play an important role in the development and course of this disease. However until today, the factual contribution of astrocytes to multiple sclerosis is elusive. Astrocytes may play an active role during degeneration and demyelination by controlling local inflammation in the CNS, provoking damage of oligodendrocytes and axons, and glial scarring but might also be beneficial by creating a permissive environment for remyelination and oligodendrocyte precursor migration, proliferation, and differentiation. Recent findings from our lab suggest that brain lipid binding protein (FABP7) is implicated in the course of multiple sclerosis and the regulation of astrocyte function. The relevance of our findings and data from other groups are highlighted and discussed in this paper in the context of myelin repair., M. Kipp ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy