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2. 3rd CCP Phenogenomics Conference 2021: abstract book: virtual conference: Vestec, 16-17 September 2021
- Creator:
- Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2021 : Vestec, Praha-západ, Česko)
- Publisher:
- Institute of Molecular Genetics of the Czech Academy of Sciences
- Format:
- electronic, electronic resource, remote, bez média, online zdroj, and 69 stran : ilustrace, převážně barevné, portréty
- Type:
- model:monograph and TEXT
- Subject:
- Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
- Language:
- English
- Description:
- Název z obálky and born digital
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
3. 4th CCP Phenogenomics Conference 2022: abstract book: hybrid conference: Vestec, 15-16 September 2022
- Creator:
- Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2022 : Vestec, Praha-západ, Česko)
- Publisher:
- Institute of Molecular Genetics of the Czech Academy of Sciences
- Format:
- electronic, electronic resource, remote, bez média, online zdroj, and 82 stran : ilustrace, převážně barevné, portréty
- Type:
- model:monograph and TEXT
- Subject:
- Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
- Language:
- English
- Description:
- Název z obálky and born digital
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
4. 8th International Symposium on Kallikreins and Kallikrein-Related Peptidases: Prague, 25-27 September 2019 : final programme & abstract book
- Creator:
- Ústav molekulární genetiky (Akademie věd ČR) and International Symposium on Kallikreins and Kallikrein-Related Peptidases 2019 : Praha, Česko)
- Publisher:
- Institute of Molecular Genetics CAS
- Format:
- electronic, electronic resource, remote, bez média, online zdroj, and 78 stran
- Type:
- model:monograph and TEXT
- Subject:
- Biochemie. Molekulární biologie. Biofyzika, molekulární genetika, enzymy, molecular genetics, enzymes, kallikrein, 577.21, 577.15, 612.015.1, 615.355, (048.3), (062.534), 2, and 577
- Language:
- English
- Description:
- Název z obálky, Obsahuje bibliografii a bibliografické odkazy, and born digital
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
5. Biotechnologický ústav
- Creator:
- Peter Šebo Peter Šebo
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Věda. Všeobecnosti. Základy vědy a kultury. Vědecká práce, Biotechnologický ústav (Akademie věd ČR), biotechnologie, molekulární genetika, inovace, biotechnology, molecular genetics, innovations, Vestec (Praha-západ, Česko), Vestec (Praha-západ, Czechia), 12, and 00
- Language:
- Czech
- Description:
- The Academy of Sciences of the Czech Republic (AS CR) established a new public research institution, the Institute of Biotechnology AS CR, v. v. i. The primary ambition of this new institute is to develop cutting-edge basic and oriented research on topics opening for diagnostic and therapeutic applicatons in human medicine. In particular, the institute was established to serve as a nucleation center of BIOCEV, the joined Biotech & Biomed Research Center of the Academy of Sciences with Charles University, to be built at Vestec near Prague by the year 2012 with the support of the European Regional Development Funds in frame of the Operational Program R&D for Innovation., Peter Šebo, -red-., and Tři otázky pro ředitele připravila -red-
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
6. CCP Phenogenomics Conference 2019: abstract book: Vestec, 12-13 September 2019
- Creator:
- Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2019 : Vestec, Praha-západ, Česko)
- Publisher:
- Institute of Molecular Genetics CAS
- Format:
- electronic, electronic resource, remote, bez média, online zdroj, and 67 stran : ilustrace, převážně barevné, portréty
- Type:
- model:monograph and TEXT
- Subject:
- Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
- Language:
- English
- Description:
- Název z obálky and born digital
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
7. Comparative analysis of tryptophan oxygenase activity and glucocorticoid receptor under the influence of insulin
- Creator:
- Isenović, Esma R., Zakula, Z., Koricanac, G., and Ribarac-Stepić, N.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Biochemie. Molekulární biologie. Biofyzika, molekulární genetika, glukokortikoidy, inzulín, tryptofan, molecular genetics, glucocorticoids, insulin, tryptophan, stability of glucocorticoid-receptor complex, tryptophan oxygenase, 2, and 577
- Language:
- English
- Description:
- This investigation addresses the interaction of insulin (INS) and glucocorticoid (GC) signaling in the hepatic regulation of tryptophan oxygenase (TO) enzyme activity in the rat. Male Wistar rats (200-250 g b.w) received an injection of the different doses of INS (10, 25, 50, 70 and 100 μg/200 g b.w., i.p.) and were used for experiments 3 h and 18 h after INS administration. This study shows that maximum of TO activity was found at dose of 50 μg of INS with peak increases observed at 3 h and 18 h after injection of INS, while INS had no effect on TO activity in adrenalectomized rats. The analysis of INS effects on glucocorticoid receptor-complex (GC/GR complex) stability shows that complexes from INS-treated rats are less stable than those from control animals. In addition, INS-stimulated stability of glucocorticoid receptor (GR) protein was significantly increased from the controls. Furthermore, the results show that GC/GR complexes from INS-treated rats could be activated and accumulated at higher rate in cell nuclei of control animals. These data support the involvement of INS in modulation of GC signaling pathway which mediates, in part, the activity of TO., E. R. Isenović, Z. Zakula, G. Koricanac, N. Ribarac-Stepić., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
8. Do nitra hmoty
- Creator:
- Luděk Svoboda
- Format:
- print, bez média, and svazek
- Type:
- article, zprávy, model:article, and TEXT
- Subject:
- Věda. Všeobecnosti. Základy vědy a kultury. Vědecká práce, Ústav molekulární genetiky (Akademie věd ČR), vědecká práce, molekulární genetika, mikroskopy, scientific work, molecular genetics, microscopes, 12, and 00
- Language:
- Czech
- Description:
- [Luděk Svoboda]. and Autor používá šifru lsd
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
9. Dostatečně starý, aby říkal, co si myslí
- Creator:
- Marina Hužvárová
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Věda. Všeobecnosti. Základy vědy a kultury. Vědecká práce, Svoboda, Jan, věda a společnost, rozhovor, molekulární genetika, genetici, osobnosti, science and society, interview, molecular genetics, geneticists, celebrities, 12, and 00
- Language:
- Czech
- Description:
- Do mozaiky dedikací letošnímu 125. výročí Akademie věd (více k 125. výročím Akademie věd ČR - Můj svět zázraků - na http://www.umenivedy.cz/) patří knižní portrét s výstižným názvem Volnomyšlenkář, dále upřesněným podtitulem Osudy a postoje molekulárního genetika Jana Svobody z pera Libuše Koubské. Vydalo Nakladatelství Academia v edici Paměť. and Marina Hužvárová.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
10. Measurement of cellular excitability by whole cell patch clamp technique
- Creator:
- Karmažínová, M. and Ľubica Lacinová
- Format:
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, genetika, molekulární genetika, genetics, molecular genetics, patch clamp, calcium current, activation, deactivation, inactivation, 14, and 612
- Language:
- English
- Description:
- Patch clamp method developed more than 30 years ago is widely used for investigation of cellular excitability manifested as transmembrane ionic current and/or generation of action potentials. This technique could be applied to measurement of ionic currents flowing through individual (single) ion channels or through the whole assembly of ion channels expressed in the whole cell. Whole cell configuration is more common for measurement of ion currents and the only one enabling measurement of action potentials. This method allows detailed analysis of mechanisms and structural determinants of voltagedependent gating of ion channels as well as regulation of channel activity by intracellular signaling pathways and pharmacological agents., M. Karmažínová, L'. Lacinová., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public