The study compiled as a part of EU prject ProAct ("Practical Regional Research and Innovation Policy in Action - the Efficient Tools for Regional Catching-up in New Member States" (Regions of Knowledge - FP6). The regional practices of innovation policy in eight EU member states are presented in case studies, elaborated for one region in each country with South Moravia representing the Czech Republic. South Moravian innovation policy is analyzed in three fundamental dimensions: strategy formation, policy deployment, and practices at the programme level. These are the constituent elements of the process that was defined by the ProAct consortium as so called "ProAct policy learning cycle". THe benchmark methodology (The ProAct Benchmarking Framework) was applied in the case studies to explore good pracices in regional innovation and research policy. In the study, the role of South Moravian Innovation Centre (JIC - Jihomoravské innovační centrum) is highlighted., Jiří Loudín, Adolf Filáček, Michal Kostka, Kateřina Tydláčková., and Obsahuje seznam literatury.