An initial exploration of in vivo hair cortisol responses to a brief pain stressor: latency, localization and independence effects

Title:

An initial exploration of in vivo hair cortisol responses to a brief pain stressor: latency, localization and independence effects

Creator:

Sharpley, Christopher F., Kauter, K. G., and McFarlane, J. R.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6410686e-aa95-494e-b838-3ccf62f12353
uuid:6410686e-aa95-494e-b838-3ccf62f12353

Subject:

Fyziologie člověka a srovnávací fyziologie, biochemie, kortizol, vlasy, stres (fyziologie), biochemistry, cortisol, hair, stress (physiology), peripheral HPA axis, 14, and 612

Type:

article, články, model:article, and TEXT

Description:

Cortisol is secreted by the central hypothalamo-pituitary-adrenal axis and affects many target organs and tissues, particularly in response to stressor demands and infection. Recent data reporting cortisol synthesis in hair follicles have shown the existence of a parallel “peripheral” HPA-axis. However, although there is evidence from in vitro studies and single-observation comparisons between groups that cortisol from hair follicles reflects endocrine changes associated with stressor demands, there are no reports to date of repeated measurements of in vivo cortisol responsivity in hair to transitory stressors. This issue was investigated with three males who underwent 1 min cold pressor test (CP). Cortisol response in hair to stressor demand appears to be (a) swift but transitory, (b) localized to the site of the demand and (c) independent of central HPA-axis activity., C. F. Sharpley, K. G. Kauter, J. R. McFarlane., and Obsahuje seznam literatury

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2009 Volume:58 | Number:5

Harvested from:

CDK

Metadata only:

false