Change in fatty acid composition of serum lipids in obese females after short-term weight-reducing regimen with the addition of n-3 long chain polyunsaturated fatty acids in comparison to controls

Title:

Change in fatty acid composition of serum lipids in obese females after short-term weight-reducing regimen with the addition of n-3 long chain polyunsaturated fatty acids in comparison to controls

Creator:

Petr Hlavatý, Marie Kunešová, Milena Gojová, Eva Tvrzická, Marek Vecka, Petr Roubal, Martin Hill, Karolína Hlavatá, Kalousková, Pavla, Vojtěch Hainer, Aleš Žák, and Jan Drbohlav

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0ac69019-4dd0-45bd-ba97-439bc720bf7a
uuid:0ac69019-4dd0-45bd-ba97-439bc720bf7a
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, endokrinologie, obezita, mastné kyseliny, redukce tělesné hmotnosti, endocrinology, obesity, fatty acids, weight loss, n-3 fatty acids, EPA, DHA, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Short-term weight-reducing regimens were shown to influence fatty acid composition of serum lipids unfavorably. Adding long chain n-3 polyunsaturated fatty acids (n-3 LC PUFA) to a low-calorie diet (LCD) could avoid these changes. The aim of this study was to examine the effect of a short-term in-patient weight-reducing regimen including LCD with yogurt enriched by low doses of n-3 PUFA (n-3 LCD). The enriched yogurt contained 790 mg of fish oil, predominantly eicosapentaenoic (20:5n-3; EPA) and docosahexaenoic (22:6n-3; DHA). Forty obese women were randomly assigned to the group consuming LCD and joghurt either with or without n-3 enrichment. Following the 3-week diet in the n-3 LCD group a significantly higher increase in the proportion of n-3 LC PUFA (sum of n-3 FA, EPA and DHA) in serum lipids was confirmed. In phospholipids (PL) a significant difference in the sum of n-6 fatty acids was found, a decrease in the n-3 LCD group and an increase in LCD group. Significantly higher increase in the PL palmitate (16:0) was shown in the LCD group. The results suggest that low doses of n-3 fatty acid enrichment can help to avoid unfavorable changes in fatty acid composition in serum lipids after a short-term weight-reducing regimen., P. Hlavatý, M. Kunešová, M. Gojová, E. Tvrzická, M. Vecka, P. Roubal, M. Hill, K. Hlavatá, P. Kalousková, V. Hainer, A. Žák, J. Drbohlav., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2008 Volume:57 | Number:Suppl 1

Harvested from:

CDK

Metadata only:

false