Postižení kognitivních funkcí (KF) je ve všech fázích roztroušené sklerózy (RS) důležitým prediktorem kvality života a je nejčastější příčinou ztráty zaměstnání. Deficit mívá nejběžněji charakter mírné kognitivní poruchy a jeho projevy jsou velmi variabilní, a proto je důležitá přesná neuropsychologická diagnostika. Mírný kognitivní deficit u RS zahrnuje obvykle zpomalení rychlosti zpracování informací, poruchu komplexní pozornosti, paměti a exekutivních funkcí. Minimalizaci dopadů onemocnění může významně ovlivnit rehabilitace kognitivních funkcí. Rehabilitace kognitivních poruch přešla od metody tužka-papír k rehabilitaci pomocí počítačových programů. Uvádíme řadu studií zabývajících se rehabilitací kognitivních funkcí včetně kvantitativních i kvalitativních výsledků jednotlivých studií a sledujeme výsledky rehabilitace v krátkodobém i dlouhodobějším horizontu. Pozitivní efekt rehabilitace se jednoznačně ukazuje v oblasti zvyšování kvality života a snižování deprese. Předmětem diskuze však zůstává, zda se nejedná jen o efekt krátkodobý, a také to, jaké další faktory mohou pozitivní efekt tréninku podpořit., In all phases of multiple sclerosis (MS), cognitive deficits (CD) are an important predictor of the quality of life and the frequent cause of job loss. The deficits usually have a character of a mild cognitive impairment and their manifestation varies greatly. Therefore, accurate neuropsychological assessment is important. Mild cognitive symptoms in MS usually include problems with the speed of information processing and visual learning, dysfunction of complex attention and executive functions. Rehabilitation of cognitive functions can significantly influence and minimize the impact of the disease. Rehabilitation of cognitive deficits has changed from “pencil-paper” method to computer-program-based rehabilitation. This papers reviews a range of studies dealing with cognitive function rehabilitation, including both quantitative and qualitative results, and both short- and long-term results. The positive effects of rehabilitation are clearly shown by increased quality of life and alleviated depressive symptoms. Further discussion is needed about durability of this effect and what other factors can positively support the training effects. Key words: multiple sclerosis – computerized cognitive training – magnetic resonance – cognitive rehabilitation – cognitive dysfunction – neuropsychological assessment The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study. The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers., and D. Chmelařová, Z. Ambler, M. Dostál, V. Vobořilová
The saccadic eye movement related potentials (SEMRPs) enable to study brain mechanisms of the sensorimotor integration. SEMRPs provide insight into various cognitive mechanisms related to planning, programming, generation and execution of the saccadic eye movements. SEMRPs can be used to investigate pathophysiological mechanisms of several disorders of the central nervous system. Here we shortly summarize basic findings concerning the significance of SEMRP components, their relationship to the functional brain asymmetry and visual attention level as well as changes related to certain neuropsychological disorders., F. Jagla, M. Jergelová, I. Riečanský., and Obsahuje bibliografii a bibliografické odkazy
Cílem přehledové studie je popsat vztah dvou proměnných – atopického ekzému a pozornosti. Nejprve je důležité vymezit dva související pojmy, které je důležité nezaměňovat, a to ADHD a ADD. Obě tyto poruchy pozornosti jsou dědičné neurovývojové poruchy. ADD se vyznačuje ztrátou soustředění, roztržitostí a emoční přecitlivělostí. ADHD je porucha pozornosti s hyperaktivitou. Vyznačuje se nepozornosti, hyperaktivitou a impulzivitou. Na základě výsledků dostupných studií, které se tímto vztahem zaobírají, je čtenáři představena daná tématika a shrnuty dosavadní poznatky. Pro přehledovou studii bylo pracováno se zdroji z dostupných vědeckých databází: PubMed, PsycInfo, Scopus a Web of Science. Pro vyhledávání byla zadána klíčová slova: atopic eczema, ADHD, ADD, attention, relationship. Dalším zvoleným kritériem pro vyhledávání bylo sledované období, které jsme stanovili bez určení, důvodem pro toto rozhodnutí bylo, že se jedná o specifickou problematiku. Studie byly vybrány na základě relevantnosti ke stanovenému cíli. Celkem se jednalo o 10 analyzovaných studií. Výsledky analyzovaných studií ukazují, že u osob s diagnostikovaným atopickým ekzémem existuje riziko poruchy pozornosti. Zároveň však nebyl prokázán přímý kauzální vztah mezi těmito proměnnými, který by v případě prokázání mohl vést ke stanovení preventivních, ale i léčebných plánů., PROBLEM: Atopic eczema is linked with several other psychosomatic diseases and disorders like sleeping disorders or low quality, chronic itching, etc. First, it is important to define two related terms that are important not to confuse, namely ADHD and ADD. Both of these attention disorders are inherited neurodevelopmental disorders. ADD is characterized by loss of concentration, distraction, and emotional hypersensitivity. ADHD is an attention deficit hyperactivity disorder. It is characterized by inattention, hyperactivity, and impulsivity. The survey study aims at describing the relation of two variables – atopic eczema and attention. Based on the results of the available studies dealing with the said relation, the topic will be presented to the reader and the existing pieces of knowledge will be summarized. METHODS: The study worked with sources from available scientific databases: PubMed, PsycInfo, Scopus and Web of Science. The following key words were entered for search: atopic eczema, ADHD, ADD, attention, relation. Another criterion selected for search was the period of observation, which we set without determination; that decision was based on the fact that the topic in question is specific. The studies were selected based on their relevance for the goal set. 10 studies were analyzed in total. RESULTS: The analysis results show that studies dealing with the issue of the effect of atopic eczema can be divided into two groups. The first group consists of studies which state, based on research, that persons with diagnosed atopic eczema are endangered by attention disorders. While comparing them with healthy population, i.e., with persons without atopic eczema, it was found that persons with atopic eczema have higher proportional chance of attention disorders, and other health problems linked with the said disease, like low quality of sleep, anxieties, depressions or behaviour disorders were registered as well. The studies under analysis also mention a risk period that may be essential for the development of attention disorder. The other group consists of studies which did not demonstrate a direct causal relation between attention eczema and attention disorders, which, if demonstrated, could lead to setting of preventive and therapeutic plans. The results of some of these studies show the coexistence of atopic eczema and ADHD, but the authors state that both disorders may not have causal relation and that they may be influenced by other factors; they recommend other studies which could clarify the prevalence of ADHD in persons with atopic eczema., and DISCUSSION AND CONCLUSION: In conclusion, it can be stated that there is a higher risk of attention disorder, ADHD, in individuals with atopic eczema. However, as studies show, a causal relation between the two variables in question has not been found yet. The results have also shown that this issue is still little explored, in spite of the fact that a number of studies had a large research set. Therefore, further extensive interdisciplinary studies are needed, in order to prove or disprove their mutual causal relation. In case of proving the causal relation, it is further recommended to proceed to determine preventive and therapeutic strategies for attention disorders caused by atopic eczema, in order to positively influence the resulting quality of life of the individuals with the said disorder type.