Search

Start Over Subject lipids

22. Sphingomyelin synthesis in helminths: a minireview

Creator:
Bankov, Ilia, Timanova, Anna, and Barrett, John
Format:
print
Type:
model:internalpart and TEXT
Subject:
lipids, sphingomyelin, parasites, helminths, and review
Language:
English
Description:
Sphingolipids are a diverse and ubiquitous group of lipids. They are widely distributed in parasites and a number of novel forms have been described. Sphingolipid synthesis has been investigated in the malarial parasite, cestodes, digencans and nematodes. Although there are differences in detail, the synthetic pathways involved are similar to those found in mammals.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

23. Štúdium fyzikálnych vlastností zmesí fosfolipidov metódou ultrazvukovej velocimetrie

Creator:
Rybár, Peter and Hianik, Tibor
Format:
print, bez média, and svazek
Type:
model:article and TEXT
Subject:
biofyzika, laserová anemometrie, lipidy, biophysics, laser velocimetry, lipids, 6, and 53
Language:
Czech
Description:
V práci sme študovali termodynamické vlastnosti lipidových dvojvrstiev veĺkých unilamelárnych vezikúl zložených z binárnych zmesí fosfatidylcholínov s rôznymi dĺžkami uhĺovodíkových reťazcov. Na štúdium bola použitá metóda merania rýchlosti a absorbcie ultrazvuku pri fixnej frekvencii (7,2 MHz). Fázové prechody dvojvrstiev zložených u čistých fosfolipidov sa vyznačovali výrazným maximom inkrementu absorbcie ultrazvuku, [αλ], kým v prípade binárnych zmesí boli pozorované dve maximá. Na základe analýzy získaných experimentálnych dát sa domnievame, že dve maximá inkrementu absorbcie [αλ] fázového prechodu binárnych lipidových zmesí môžu odrážať existenciu dvoch separovaných fáz, spôsobených neideálnou miešateĺnosťou molekúl oboch komponent. Existencia dvoch absorpčnych píkov môže odrážať aj efekty formovania klastrov v lipidovej dvojvrstve počas procesu fázového prechodu. Na základe vypočítaných hodnôt veĺkostí kooperatívnych jednotiek môžeme usudzovať o veĺkosti laterálnej fázovej separácie jednotlivých komponent binárnych lipidových zmesí. Z tvaru teplotných závislostí [αλ] pre binárne lipicové zmesi je možné predpokladať, že ich fázový prechod je daný lineárnou kombináciou fázových prechodov (absorbčných píkov) jednotlivých lipidových komponent., Peter Rybár, Tibor Hianik., and Obsahuje seznam literatury
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

24. The kind of AKH-mobilized energy substrates in insects can be predicted without a knowledge of the hormone structure

Creator:
Socha , Radimír, Kodrík, Dalibor , Šimek, Petr, and Patočková , Markéta
Type:
article, model:article, and TEXT
Subject:
Adipokinetic hormones, Dysdercus cingulatus, Pyrrhocoris apterus, Locusta migratoria, Tenebrio molitor, Pyrap-AKH, lipids, carbohydrates, and structure-function relations
Language:
English
Description:
The aim of this study was to show that the kind of AKH-mobilized energy substrates in insects can be predicted on the basis of the results obtained with the application of heterologous, i.e. inter-species, AKHs. Four different AKHs, the Locmi-AKH-I inducing hyperlipaemia and hyperglycaemia in Locusta migratoria, Tenmo-HrTH inducing hyperglycaemia in Tenebrio molitor, and Pyrap-AKH and Peram-CAH-II inducing hyperlipaemia in Pyrrhocoris apterus were used, firstly in conspecific tests, secondly in all possible species-AKH combinations, and finally in individual applications on the test species, the cotton bug Dysdercus cingulatus. Since each of the AKHs induced hyperlipaemia in D. cingulatus adults, we predicted that lipids are the only energy substrates which are mobilized in this species by its native AKH. The accuracy of this prediction was subsequently confirmed by the structural identification of the native D. cingulatus AKH and conspecific application tests. The proposed methodical approach can serve as a suitable monitoring system for determination of the kind of energy substrates mobilized by native insect AKHs until the structure of the hormone is identified.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

25. ZBTB16 gene variability influences obesity-related parameters and serum lipid levels in Czech adults

Creator:
Běla Bendlová, Marie Vaňková, Hill, M., Vacínová, G., Petra Lukášová, Daniela Vejražková, Lucie Šedová, Ondřej Šeda, and Josef Včelák
Format:
print, bez média, and svazek
Type:
article, články, journal articles, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, lipidy, lipids, body fat distribution, ZBTB16, multivariate regression, body mass index, 14, and 612
Language:
English
Description:
The data derived from rat models and the preliminary results of human studies provide strong indices of involvement of common ZBTB16 variants in a range of cardiovascular and metabolic traits. This cross-sectional study in the Caucasian cohort of 1517 Czech adults aimed to verify the hypothesis that ZBTB16 gene variation directly affects obesity and serum lipid levels. Genotyping of nine polymorphisms of the ZBTB16 gene (rs11214863, rs593731, rs763857, rs2846027, rs681200, rs686989, rs661223, rs675044, rs567057) was performed. A multivariate bidirectional regression with the reduction of dimensionality (O2PLS model) revealed relationships between basal lipid levels and anthropometric parameters and some minor ZBTB16 alleles. In men, the predictors - age and presence of minor ZBTB16 alleles of rs686989, rs661223, rs675044, rs567057 - were associated with significantly higher body mass index, waist to hip ratio, body adiposity index, waist and abdominal circumferences, higher total cholesterol and LDL cholesterol and explained 20 % of variability of these variables. In women, the predictors - age and presence of the rs686989 minor T allele - were also associated with increased anthropometric parameters and total cholesterol and LDL cholesterol but the obtained O2PLS model explained only 7.8 % of the variability of the explained variables. Our study confirmed that the selected gene variants of the transcription factor ZBTB16 influence the obesity-related parameters and lipid levels. This effect was more pronounced in men., B. Bendlová, M. Vaňková, M. Hill, G. Vacínová, P. Lukášová, D. Vejražková, L. Šedová, O. Šeda, J. Včelák., and Obsahuje bibliografii
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public