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5462. Borrelia-infection rates in tick and insect vectors accompanying human risk of acquiring Lyme borreliosis in a highly endemic region in Central Europe
- Creator:
- Zeman, Petr
- Format:
- Type:
- model:internalpart and TEXT
- Subject:
- Lyme borreliosis, retrospective epidemiological data, statistical mapping, arthropod vectors, direct immunofluorescence assay, correlation, Central Bohemia, and geographical information system (GIS)
- Language:
- English
- Description:
- The methods of spatial statistics were applied to assess the geographical pattern of risk of Lyme borreliosis in Central Bohemia, the Czech Republic, based on retrospective data on disease contractions. The statistical risk was then compared at 15 selected localities with the infection challenge presented by ticks and insects carrying borreliae. Over 5,000 Ixodes ricinus (L.) ticks and 390 hacmatophagous dipterans were screened by direct immunofluorescence method, and the spatial and seasonal variance of infection rates were studied. Infected ticks were found at each locality throughout the warm season; in nymphs, sample infection rates ranged from 4.9% to 23.1% with a mean of 14.5% in spring, from 7.7% to 28.7% with a mean of 16.1% in summer, and from 7% to 20.6% with a mean of 13.6% in autumn. The statistical risk was found to correlate well with an average nymphal infection challenge, i.e. I. ricinus nymphal abundance x infection rate, at a given locality. Statistically significant cumulation of insect-history recalling patients into several, generally wetland, areas was ascertained; borreliae were revealed in 0.5% of the dipterans examined.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
5463. Bosentan normalizes the GFR response to renal nerve stimulation following reversible unilateral ureteric obstruction in the rat
- Creator:
- Hammad, F. T., Wheatley, A. M., and Davis, G.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, ureteric obstruction, renal nerve stimulation, bosentan, 14, and 612
- Language:
- English
- Description:
- We investigated the renal response to direct renal nerve stimulation, 2 weeks following reversal of 24-h unilateral (left) ureteric obstruction. Renal nerve stimulation caused a 13-15 % fall in renal blood flow, in 4 groups of anesthetized rats following ureteric obstruction (n=9) or a sham operation (n=7) both with (n=9) and without (n=7) treatment with the mixed ETA/B receptor antagonist, bosentan. In the sham-operated rats, renal nerve stimulation did not change glomerular filtration rate but reduced urine flow rate (37±3 %, P<0.001), and absolute (38±4 %, P<0.001) and fractional (35±5 %, P<0.01) sodium excretion. Following unilateral ureteric obstruction, renal nerve stimulation increased glomerular filtration rate by 22±3 % (P<0.01), but reduced urine flow rate (14±2 %, P<0.001) and fractional sodium excretion (23±5 %, P<0.01). Bosentan treatment had no effect on baseline or renal responses to renal nerve stimulation in the sham group but normalized the renal response to renal nerve stimulation in the unilateral ureteric obstruction group. We conclude that 14 days after a 24-h period of unilateral ureteric obstruction there is an increase in GFR in response to direct renal nerve stimulation, which is due, in part, to the actions of endothelin at the time of obstruction., F. T. Hammad, A. M. Wheatley, G. Davis., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
5464. Boskovice - město sedmizubého hřebene =
- Publisher:
- Město Boskovice ve spolupráci s MP Holding v nakl. Albert,
- Type:
- monografie
- Subject:
- Geografie Česka a Slovenska, reálie, cestování, města, dějiny měst, přehledná zpracování dějin českých zemí (chronologicky), and města, obce
- Language:
- Czech, English, and German
- Description:
- 1000 výt.
- Rights:
- unknown
5465. Boskovice synagogue :
- Creator:
- Sixtová, Olga,
- Type:
- text, statický obraz, and průvodce
- Subject:
- Architektura, synagogy, památky architektonické, přehledná zpracování dějin českých zemí (chronologicky), židovské památky, hřbitovy, synagogy, and jednotlivé památky, památkové rezervace
- Language:
- English
- Description:
- Přeloženo z češtiny
- Rights:
- unknown
5466. Boskovice v historických fotografiích a pohlednicích /
- Creator:
- Filip, Vladimír,
- Type:
- text, statický obraz, and publikace fotografické
- Subject:
- Geografie Česka a Slovenska, reálie, cestování, města, fotografie historické, pohlednice historické, české země 1848-1918, Československo 1918-1992, města, obce, and divadlo, film, fotografie
- Language:
- Czech, English, and German
- Description:
- Hřbetní název: Boskovice
- Rights:
- unknown
5467. Bosnia and Herzegovina under the Communist Regime: an Outlook on Educational Policy /
- Creator:
- Šušnjara, Snjezana
- Type:
- text and studie
- Language:
- English
- Rights:
- unknown
5468. Bosnia, Bosnian Czechs and Migratory Bridges /
- Creator:
- Uherek, Zdeněk,
- Publisher:
- Institute of Ethnology,
- Subject:
- Češi bosenští, migrace, menšiny národnostní, světové dějiny 1789-1918, světové dějiny od r. 1918 do současnosti, Bosna a Hercegovina, Jugoslávie, migrace, vystěhovalectví, kolonizace, české země 1848-1918, and Československo 1918-1992
- Language:
- English
- Rights:
- unknown
5469. Bosnian Study on Markers of Ischaemic Stroke in Adults 20–50 Years Old (SMISAO): preliminary report
- Creator:
- Mahmutbegovic, N., Mehicevic, A., Adler, G., Omerhodzic, I., Mahmutbegovic, E., Valjevac, A., Borecki, K., and Mehmedika Suljic, E.
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- stroke, young adults, risk factors, and SNPs
- Language:
- English
- Description:
- Previous research suggested that several genetic polymorphisms are associated with increased risk of ischaemic stroke (IS) in young adults. However, the predictive biomarkers of IS in young adults are still unclear. Our aim was to assess the contribution of modifiable and genetic factors in IS in young adults. In total, 40 stroke patients and 40 healthy controls aged 20 to 50 years were recruited. Data on modifiable factors were collected, then participants were genotyped for seven SNPs linked to thrombophilia: ACE rs1799752, PAI-1 rs1799889, APOE rs1412 and rs429358, FV rs6025 and rs1800595, and FII rs62623459. Significantly increased risk factors: hypertension and dyslipidaemia in stroke patients compared with the controls: 50.0 % vs 27.5 % and 75.0 % vs 40.0% (P = 0.039 and P = 0.002, respectively) were observed. Stroke patients compared with controls did not differ in distribution of ACE, APOE, FV, and FII variants. The 4G4G homozygotes of the PAI-1 gene were significantly more prevalent in stroke patients compared to the controls: 42.5 % vs 17.5 %, (P = 0.033). In the group with the small vessel occlusion subtype of stroke, statistically significant overrepresentation of 4G4G homozygotes and frequency of the 4G allele compared with controls: 57.1 % vs 17.5 % and 0.7 vs 0.45 (P = 0.026 and P = 0.03, respectively) were observed. Independent predictors of stroke incident were: dyslipidaemia (OR (95% CI) = 4.2 (1.4–12.4)) and 4G4G genotype (OR (95% CI) = 3.9 (1.1–13.7)). These results confirm the contribution of dyslipidaemia and 4G4G genotype in the increased risk of IS in young Bosnian adults.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
5470. Bosworth-Toller’s Anglo-Saxon Dictionary online
- Creator:
- Tichý, Ondřej, Roček, Martin, Bočková, Renata, Čermák, Matěj, Dragounová, Jolana, Filipová, Helena, Gilová, Lucie, Hejná, Michaela, Hladíková, Lenka, Hladká, Alena, Hubinová, Veronika, Krajcsovicsová, Vlaďena, Kupková, Tatiana, Lebedeva, Tatiana, Malečková, Nikola, Novotná, Alena, Pazderová, Tereza, Popelíková, Jiřina, Rumlová, Jana, Tyčová Ocelík, Dana, Volná, Veronika, and Zahradníková, Tereza
- Publisher:
- Charles University, Faculty of Arts, Department of English Language and ELT Methodology
- Type:
- text, lexicon, and lexicalConceptualResource
- Subject:
- English, Old English, Anglo-Saxon, dictionary, Bosworth, Toller, lexicography, digitalization, English history, Mediaeval, and Medieval
- Language:
- English, Old English (ca. 450-1100), Latin, Ancient Greek (to 1453), and Ancient Hebrew
- Description:
- Description : This is an online edition of An Anglo-Saxon Dictionary, or a dictionary of "Old English". The dictionary records the state of the English language as it was used between ca. 700-1100 AD by the Anglo-Saxon inhabitants of the British Isles. This project is based on a digital edition of An Anglo-Saxon dictionary, based on the manuscript collections of the late Joseph Bosworth (the so called Main Volume, first edition 1898) and its Supplement (first edition 1921), edited by Joseph Bosworth and T. Northcote Toller, today the largest complete dictionary of Old English (one day to be hopefully supplanted by the DOE). Alistair Campbell's "enlarged addenda and corrigenda" from 1972 are not public domain and are therefore not part of the online dictionary. Please see the front & back matter of the paper dictionary for further information, prefaces and lists of references & contractions. The digitization project was initiated by Sean Crist in 2001 as a part of his Germanic Lexicon Project and many individuals and institutions have contributed to this project. Check out the original GLP webpage and the old Bosworth-Toller offline application webpage (to be updated). Currently the project is hosted by the Faculty of Arts, Charles University. In 2010, the data from the GLP were converted to create the current site. Care was taken to preserve the typography of the original dictionary, but also provide a modern, user friendly interface for contemporary users. In 2013, the entries were structurally re-tagged and the original typography was abandoned, though the immediate access to the scans of the paper dictionary was preserved. Our aim is to reach beyond a simple digital edition and create an online environment dedicated to all interested in Old English and Anglo-Saxon culture. Feel free to join in the editing of the Dictionary, commenting on its numerous entries or participating in the discussions at our forums. We hope that by drawing the attention of the community of Anglo-Saxonists to our site and joining our resources, we may create a more useful tool for everybody. The most immediate project to draw on the corrected and tagged data of the Dictionary is a Morphological Analyzer of Old English (currently under development). We are grateful for the generous support of the Charles University Grant Agency and for the free hosting at the Faculty of Arts at Charles University. The site is currently maintained and developed by Ondrej Tichy et al. at the Department of English Language and ELT Methodology, Faculty of Arts, Charles University in Prague (Czech Republic).
- Rights:
- Creative Commons - Attribution 4.0 International (CC BY 4.0), http://creativecommons.org/licenses/by/4.0/, and PUB