Let $\Lambda=\left(\begin{smallmatrix} A&M 0&B \end{smallmatrix}\right)$ be an Artin algebra. In view of the characterization of finitely generated Gorenstein injective $\Lambda$-modules under the condition that $M$ is a cocompatible $(A,B)$-bimodule, we establish a recollement of the stable category $\overline{\rm Ginj(\Lambda)}$. We also determine all strongly complete injective resolutions and all strongly Gorenstein injective modules over $\Lambda$., Chao Wang, Xiaoyan Yang., and Obsahuje bibliografii
The acidic tumor microenvironment (TME) of pancreatic cancer affects the physiological function of pancreatic stellate cells (PSCs), which in turn promotes cancer progression. Acid-sensing ion channel 1a (ASIC1a) is responsible for acidosis-related physiopathological processes. In this study, we investigated the effect of acid exposure on the activation and autophagy of PSCs, and the role of ASIC1a in these events. The results showed that acidic medium upregulated the expression of ASIC1a, induced PSCs activation and autophagy, which can be suppressed by inhibiting ASIC1a using PcTx1 or ASIC1a knockdown, suggesting that ASIC1a involves these two processes. In addition, the acidinduced activation of PSCs was impaired after the application of autophagy inhibitor alone or in combination with ASIC1a siRNA, meaning a connection between autophagy and activation. Collectively, our study provides evidence for the involvement of ASIC1a in the acid-caused PSCs activation, which may be associated with autophagy induction.
Interception is one of the most underestimated processes in hydrological cycle in arid and semiarid regions. In Qilian Mountains of northwestern arid and semiarid China, the Qinghai spruce (Picea crassifolia) forest plays an important role in the hydrological cycle of the inland Heihe River basin. The historical disturbance of Qinghai spruce forest has resulted in various ecological problems. In order to realize the sustainable development of Heihe River basin, the Chinese government implemented restoration practices for Qinghai spruce in the past three decades. In this study, we estimated the rainfall interception in the actual and potential distribution of Qinghai spruce forest. Some of the important findings include: (1) The interception ratio of rainfall events ranged from 11-51% with a mean value of 27.02%; (2) Totally, 147 Mt of rainfall is intercepted by canopy of actual Qinghai spruce forest, in the projected potential distribution of the forest, totally 407 Mt of rainfall will be intercepted.