1. Oesophageal manometry in experimental pigs: methods and initial experience
- Creator:
- Tachecí, Ilja, Radochová, Věra, Květina, Jaroslav, Rejchrt, Stanislav, Kopáčová, Marcela, and Bureš, Jan
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT
- Subject:
- celková anestezie, zvířata, dolní jícnový svěrač--fyziologie, ezofágus--fyziologie, ženské pohlaví, mužské pohlaví, manometrie--metody, modely u zvířat, tlak, and Sus scrofa
- Language:
- English
- Description:
- The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable with healthy human subjects. Evocable swallowing is doable and oesophageal peristalsis is quantifiable. Basic manometric parameters were different in male and female animals. Oesophageal manometry in experimental pigs is feasible. Porcine oesophageal manometry will be usable for preclinical studies in future. and I. Tachecí, V. Radochová, J. Květina, S. Rejchrt, M. Kopáčová, J. Bureš
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public