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Start Over Creator Lukášová, E.

1. Estimation of apoptosis in C6 glioma cells treated with antidepressants

Creator:
Španová, A., Kovářů, H., Lisá, V., Lukášová, E., and Rittich, B.
Type:
article, model:article, and TEXT
Subject:
glioma cells, antidepressants, DNA fragmentation, and apoptosis
Language:
English
Description:
Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine). Some discrete bands containing a population of short DNA fragments appeared after 1 and 5 days of cultivation. Apoptotic DNA breaks were verified at single cell level using the TUNEL test in cells treated with fluoxetine.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public