Estimation of apoptosis in C6 glioma cells treated with antidepressants

Title:

Estimation of apoptosis in C6 glioma cells treated with antidepressants

Creator:

Španová, A., Kovářů, H., Lisá, V., Lukášová, E., and Rittich, B.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:d414004f-b68f-495d-acf4-db427dd6fea8
uuid:d414004f-b68f-495d-acf4-db427dd6fea8

Subject:

glioma cells, antidepressants, DNA fragmentation, and apoptosis

Type:

article, model:article, and TEXT

Description:

Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine). Some discrete bands containing a population of short DNA fragments appeared after 1 and 5 days of cultivation. Apoptotic DNA breaks were verified at single cell level using the TUNEL test in cells treated with fluoxetine.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1997 Volume:46 | Number:2

Harvested from:

CDK

Metadata only:

false