The impact of selected dytokines in the follow-up of normal pressure hydrocephalus

Title:

The impact of selected dytokines in the follow-up of normal pressure hydrocephalus

Creator:

Sosvorova, L., Milan Mohapl, Josef Včelák, Hill, M., Vítků, J., and Richard Hampl

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:f5573488-aee5-4a68-aae5-2090017d414e
uuid:f5573488-aee5-4a68-aae5-2090017d414e
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, cytokiny, mozkomíšní mok, neurodegenerace, cytokines, cerebrospinal fluid, neurodegeneration, normal pressure hydrocephalus, ventriculoperitoneal shung, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Cytokines are widely known mediators of inflammation accompanying many neurodegenerative disorders including normal pressure hydrocephalus (NPH). NPH is caused by impaired cerebrospinal fluid (CSF) reabsorption and treated by surgical shunt insertion. The diagnostics is still complicated and the shunt effect is not durable; after several years, dementia may develop. In the clinical practice, biomarkers support the diagnostics as well as the further time course of many neurodegenerative diseases. Until recently, no reliable biomarker for NPH was evaluated. The attempt of this review was to make a survey concerning cytokines as possible NPH markers. Among all reviewed cytokines, the most promising are CSF IL-10 and IL-33, enabling to follow-up the disease progression and monitoring the effectiveness of the shunt insertion., L. Sosvorova, M. Mohapl, J. Vcelak, M. Hill, J. Vitku, R. Hampl., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false