Chloride cotransport in the membrane of earthworm body wall muscles

Title:

Chloride cotransport in the membrane of earthworm body wall muscles

Creator:

Volkov, E. M., Nurullin, L. F., Nikolsky, E., Jan Krůšek, and František Vyskočil

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:f3b5464a-15cc-419a-a645-e1b6d7a047de
uuid:f3b5464a-15cc-419a-a645-e1b6d7a047de
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, žížaly, earthworms, resting membrane potential, NA+-K+-ATPase, ouabain, furosemide, chloride transporter, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The resting membrane potential (Vm) of isolated somatic longitudinal muscles of the earthworm Lumbricus terrestris was studied by glass microelectrodes. The inhibition of chloride permeability by low pH did not affect Vm of the muscle fibers in isolated somatic longitudinal muscles of the earthworm Lumbricus terrestris which was -48.7 mV (inside negative) at pH 7.3 and -49.1 at pH 5.6. On the other hand, bathing the muscles in Cl- and Na+-free solutions, or application of the chloride transporter inhibitor furosemide and Na+-K+-ATPase inhibitor ouabain depolarized the Vm by 3-5 mV. The effects of a Cl- -free solution and ouabain were not additive. This demonstrates relatively small contribution of equilibrium potential for Cl- to the resting membrane potential and electrogenic effect of Na+K+-ATPase which is dependent on the supply of Na+i ions by furosemide-sensitive and Cl-e- and Na+e-dependent electroneutral transport (most probably Na+K+Cl- cotransport)., E. M. Volkov, L. F. Nurullin, E. Nikolsky, J. Krůšek, F. Vyskočil., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:5

Harvested from:

CDK

Metadata only:

false