Participation of electrogenic Na+-K+-ATPase in the membrane potential of earthworm body wall muscles

Title:

Participation of electrogenic Na+-K+-ATPase in the membrane potential of earthworm body wall muscles

Creator:

Volkov, E. M., Nurullin, L. F., Ivana Švandová, Nikolsky, E. E., and František Vyskočil

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:da6abe8e-b7e6-4f59-a23d-8c3f5e8eb250
uuid:da6abe8e-b7e6-4f59-a23d-8c3f5e8eb250
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, žížaly, žáby, earthworms, frogs, Na+-K+-ATPase, resting membrane potential, ouabain, 14, and 612

Type:

article, články, journal articles, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The effect of Na+-K+-ATPase inhibitor ouabain on the resting membrane potential (Vm) was studied by glass microelectrodes in isolated somatic longitudinal muscles of the earthworm Lumbricus terrestris and compared with frog sartorius muscle. In earthworm muscle, Vm was -49 mV (inside negative) in a reference external solution with 4 mmol/l K+. The electrogenic participation of Na+-K+-ATPase was absent in solutions with very low concentrations of 0.01 mmol/l K+, higher in 4 and 8 mmol/l K+ (4-5 mV) and maximal (13 mV) in solutions containing 12 mmol/l K+ where Vm was -46 mV in the absence and -33 mV in the presence of 1x10-4 M ouabain. The electrogenic participation of Na+-K+-ATPase was much smaller in m. sartorius of the frog Rana temporaria bathed in 8 and 12 mmol/l K+. The results indicate that the Na+-K+-ATPase is an important electrogenic factor in earthworm longitudinal muscle fibres and that its contribution to Vm depends directly on the concentration of K+ in the bathing solution., E. M. Volkov, L. F. Nurullin, I. Švandová, E. E. Nikolsky, F. Vyskočil., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2000 Volume:49 | Number:4

Harvested from:

CDK

Metadata only:

false