Sleep apnoea in patients with nocturnal hypertension: a multicenter study in the Czech Republic

Title:

Sleep apnoea in patients with nocturnal hypertension: a multicenter study in the Czech Republic

Creator:

Milada Hobzová, Karel Šonka, Vítězslav Kolek, Placková, M, Jitka Zapletalová, Radvanský, M, Eva Kriegová, Jan Václavík, and Martin Pretl

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:d62b0587-13c0-4c00-820a-460635b61883
uuid:d62b0587-13c0-4c00-820a-460635b61883
issn:0862-8408

Subject:

fyziologie člověka, human physiology, Sleep apnoea, Nocturnal hypertension, Ambulatory blood pressure monitoring, Mallampati score, Epworth sleepiness scale, BMI, 14, and 612

Type:

model:article and TEXT

Format:

print, bez média, and svazek

Description:

Sleep apnoea (SA) is common in patients with hypertension. Nowadays, limited data on the prevalence of SA in nocturnal hypertension (NH) exist. Therefore, we studied the occurrence of SA in Czech patients and its association with 24-h ambulatory blood pressure monitoring (ABPM), breathing disturbances in sleep, anthropometric data, Mallampati score and Epworth sleepiness scale (ESS) using the Apnea Link device. Undiagnosed SA was found in 72.9 % patients (29.3 % mild, 26.6 % moderate, 17.0 % severe) of 188 patients with NH measured by ABPM. The median of the apnoea-hypopnoea index (AHI) was 12.0 (25th-75th percentile 5.0-23.8). Moderate/severe SA (AHI≥15) was associated with BMI, waist circumference, mean night saturation (SpO2), t90, oxygen desaturation index (ODI), ESS (daytime BP only) (p≤0.032), but not ABPM parameters and Mallampati score (p>0.09). A likelihood of moderate/severe SA was enhanced by ODI>14.5 events/h (odds ratio=57.49, 95 % CI=22.79-145.01), t90>6.5 % (8.07, 4.09-15.92), mean night SpO2<93.5 % (3.55, 1.92-6.59), BMI>29.05 kg/m2 (6.22, 3.10-12.49), circum waist>105.5 cm (3.73, 1.57-8.83), but not by any ABPM parameter. In conclusion, a high incidence of SA (72.9 %) was observed in Czech patients with NH. SA severity was associated with body characteristics and oxygenation parameters, but not with ABMP parameters and Mallampati score., M. Hobzová, K. Šonka, M. Pretl, J. Václavík, E. Kriegová, M. Radvanský, J. Zapletalová, M. Placková, V. Kolek., and Seznam literatury

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:2

Harvested from:

CDK

Metadata only:

false