Age-dependent changes of baroreflex efficiency in dahl rats: effects of high salt intake

Title:

Age-dependent changes of baroreflex efficiency in dahl rats: effects of high salt intake

Creator:

Nedvídek, J. and Zicha, J.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:d1f43bb8-9a6f-4d29-a2d8-d2242773d808
uuid:d1f43bb8-9a6f-4d29-a2d8-d2242773d808

Subject:

baroreflex, heart rate, mean arterial pressure, age, salt intake, and phenylephrine

Type:

article, model:article, and TEXT

Description:

The age-dependent changes in baroreflex control of heart rate were studied in inbred Dahl rats. At the age of 8 weeks the baroreflex slope was significantly greater in salt-resistant (R/Jr) than in salt-sensitive (S/Jr) rats fed a low- salt diet. The reverse was true in 16-week-old animals. High salt intake (8 % NaCI diet for 4 weeks) suppressed baroreflex efficiency in both age groups of S/Jr animals whereas no effects occurred in R/Jr rats. Baroreflex slope was, however, significantly lower in young S/Jr rats with a severe form of salt hypertension than in adult salt-loaded S/Jr rats in which only a moderate blood pressure elevation was observed.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1993 Volume:42 | Number:3

Harvested from:

CDK

Metadata only:

false