Carnitine pretreatment can partially change the excitability of the immature nervous tissue

Title:

Carnitine pretreatment can partially change the excitability of the immature nervous tissue

Creator:

Dana Marešová, Hana Rauchová, and Kateřina Jandová

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:c820cccb-ba1a-491a-913b-84e9a4fcc74f
uuid:c820cccb-ba1a-491a-913b-84e9a4fcc74f
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, epileptické záchvaty, epileptic seizures, carnitine treatment, hypobaric hypoxia, neuronal excitability, rat, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The possible protective action of L-carnitine on neuronal excitability was studied in 21-day-old male Wistar rats with implanted electrodes. Administration of L-carnitine did not change the elicitation and duration of the epileptic seizures (cortical afterdischarges, ADs) in rats under normobaric oxygen atmosphere conditions. However, in animals exposed to 30 min hypobaric hypoxia the duration of the ADs was shortened after the second, fourth and sixth stimulation (in comparison with the first evoked ADs) while carnitine-treated rats retained their neuronal excitability and the duration of ADs was shortened only after the third stimulation., D. Marešová, H. Rauchová, K. Jandová, I. Valkounová, J. Koudelová, S. Trojan., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2001 Volume:50 | Number:4

Harvested from:

CDK

Metadata only:

false