Short-term arterial compliance changes in the context of systolic blood pressure influence

Title:

Short-term arterial compliance changes in the context of systolic blood pressure influence

Creator:

Svec, David, Czippelova, Barbora, Cernanova Krohova, Jana, Mazgutova, Nikoleta, Wiszt, Radovan, Turianikova, Zuzana, Matuskova, Lenka, and Javorka, Michal

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bf6dd61b-a90e-447c-b067-8029bb0ccaff
uuid:bf6dd61b-a90e-447c-b067-8029bb0ccaff
doi:10.33549/physiolres.934838

Subject:

arterial compliance, systolic pressure, total peripheral resistance, head-up tilt, and mental stress

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

Arterial compliance (C) is a complex parameter influencing ventricular-arterial coupling depending on structural (arterial wall remodeling) and functional (blood pressure, smooth muscles tone) changes. Based on Windkessel model, C can be calculated as the ratio of a time constant Tau characterizing diastolic blood pressure decay and total peripheral resistance (TPR). The aim of this study was to assess changes of C in the context of systolic arterial pressure (SAP) perturbations during four physiological states (supine rest, head-up tilt, supine recovery, mental arithmetic). In order to compare pressure independent changes of C a new index of C120 was proposed predicting C value at 120 mm Hg of SAP. Eighty-one healthy young subjects (48 f, average age 18.6 years) were examined. Hemodynamic parameters were measured beat-to-beat using volume-clamp photoplethysmographic method and impedance cardiography. We observed that C was strongly related to SAP values on the beat-to-beat time scale. Interestingly, C120 decreased significantly during stress phases. In conclusion, potential changes of SAP should be considered when measuring C. Arterial compliance changes in the opposite direction to TPR pointing towards influence of vascular tone changes on its value.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

S339-S348

Source:

Physiological research | 2021 Volume:70 | Number:Supplement 3

Harvested from:

CDK

Metadata only:

false