Androgens in women: critical evaluation of the methods for their determination in diagnostics of endocrine disorders

Title:

Androgens in women: critical evaluation of the methods for their determination in diagnostics of endocrine disorders

Creator:

Michaela Dušková, Lucie Kolátorová Sosvorová, and Luboslav Stárka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:a0c2c396-76b8-4585-8607-b224cd19a182
uuid:a0c2c396-76b8-4585-8607-b224cd19a182
issn:0862-8408

Subject:

testosteron, testosterone, direct immunoassay, LC-MS, androstenedione, DHEA(S), RIA with extraction, 14, and 612

Type:

model:article and TEXT

Format:

print, bez média, and svazek

Description:

The androgens dehydroepiandrosterone sulfate, dehydroepiandrosterone, androstenedione and testosterone are routinely assessed in women, and circulating levels of these androgens reflect their production. These androgens are measured in most laboratories using various immuno-analytical methods. Recently, however, androgen assays have begun to be performed using gas or liquid chromatography combined with mass spectrometry. To better understand the difficulties and issues of androgen laboratory diagnostics, it is important to assess each of the methods used, how and why they were introduced into practice, and their advantages, limits, historic milestones and current status. It is also necessary to understand how reference ranges are determined and specifics arising from the physiology of individual androgens. Here we present a summary and discussion of these issues., M. Dušková, L. Kolátorová, L. Stárka., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:Suppl 3

Harvested from:

CDK

Metadata only:

false