Immunity - a significant pathogenic factor as well as an integral part of the psychoneuroendocrine-immune regulations

Title:

Immunity - a significant pathogenic factor as well as an integral part of the psychoneuroendocrine-immune regulations

Creator:

František Vožeh

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:9a818169-fb10-49ed-8213-27c8525e015a
uuid:9a818169-fb10-49ed-8213-27c8525e015a
issn:0862-8408

Subject:

fyziologie člověka, human physiology, Immunity, Pathogenesis, Psychoneuroimmunology, Psychoneuroendocrine-immune regulations, Stress diseases, 14, and 612

Type:

model:article and TEXT

Format:

print, bez média, and svazek

Description:

Immunity plays an important role in the reactivity of the organism and, in this context, is an essential factor in the pathogenesis of many diseases. Basically, there is no system or organ in the body, whose dysfunction is not related to immunity consequences. In addition, there are also multisystem diseases simultaneously involving multiple body systems. They are not always caused by weak immunity, but also often by modified immune reactions known as overshooting. The essence of all these diseases is a change in the reactivity of the organism where immunity plays an important role. The immunity as such is then part of the systems of neuroendocrine-immune regulation, which have common mediators and receptors. The establishment of psychoneuroimmunology, a relatively new discipline in neuroscience, contributed to a detailed understanding of these mechanisms between central and peripheral nervous system, the endocrine system and the immune system. This research enabled the uncovering of the nature of stress-diseases and impact of other regulatory disturbances on the function of various body organs and systems of the organism as a whole. The aim of this short review is to show complex interconnections of these relationships to better understand the human health and disease., F. Vožeh., and Seznam literatury

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:2

Harvested from:

CDK

Metadata only:

false