Higher levels of salivary α-amylase predict failure of cessation efforts in male smokers

Title:

Higher levels of salivary α-amylase predict failure of cessation efforts in male smokers

Creator:

Michaela Dušková, Kateřina Šimůnková, Martin Hill, Hruškovičová, H., Petra Hoskovcová, Eva Králíková, and Luboslav Stárka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0b770cf1-d392-46a4-a21d-e8c2a754677f
uuid:0b770cf1-d392-46a4-a21d-e8c2a754677f

Subject:

Fyziologie člověka a srovnávací fyziologie, predikce, odvykání kouření, stres (fyziologie), prediction, smoking cessation, stress (physiology), salivary α-amylase, salivary cortisol, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print

Description:

The ability to predict the success or failure of smoking cessation efforts will be useful for clinical practice. Stress response is regulated by two primary neuroendocrine systems. Salivary cortisol has been used as a marker for the hypothalamuspituitary- adrenocortical axis and salivary α-amylase as a marker for the sympathetic adrenomedullary system. We studied 62 chronic smokers (34 women and 28 men with an average age of 45.2±12.9 years). The levels of salivary cortisol and salivary α-amylase were measured during the period of active smoking, and 6 weeks and 24 weeks after quitting. We analyzed the men separately from the women. The men who were unsuccessful in cessation showed significantly higher levels of salivary α-amylase over the entire course of the cessation attempt. Before stopping smoking, salivary cortisol levels were higher among the men who were unsuccessful in smoking cessation. After quitting, there were no differences between this group and the men who were successful in cessation. In women we found no differences between groups of successful and unsuccessful ex-smokers during cessation. In conclusions, increased levels of salivary α-amylase before and during smoking cessation may predict failure to quit in men. On the other hand, no advantage was found in predicting the failure to quit in women. The results of our study support previously described gender differences in smoking cessation., M. Dušková ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2010 Volume:59 | Number:5

Harvested from:

CDK

Metadata only:

false