Modification of organ protein synthesis after surgical stress by low energy diets with different lipid/glucose ratios

Title:

Modification of organ protein synthesis after surgical stress by low energy diets with different lipid/glucose ratios

Creator:

López-Hellin, J., Garcia-Arumi, E., Farriol, M., Arbos, M. A., Andreu, A. L., and S., Schwartz

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0b246c35-1a55-4a11-9700-5c6786d17f78
uuid:0b246c35-1a55-4a11-9700-5c6786d17f78

Subject:

hypocaloric nutrition, parenteral nutrition, protein synthesis, liver, and jejunal mucosa

Type:

article, model:article, and TEXT

Description:

The aim of this work was to study the effects of low energy parenteral diets with different lipid/glucose ratios on rat liver and jejunal mucosa protein synthesis. The studied diets were: LO (100 % glucose, control diet), L25 (25 % lipids: 75 % glucose), L50 (50 % lipids: 50 % glucose) and L75 (75 % lipids: 25 % glucose). All diets were isoenergetic and isonitrogenated, with a standard amino acid content. The diets were assayed in 93 rats with open femoral fracture immobilized by Kirschner pin insertion. The diets were administered for 4 days. On the fifth day, liver and jejunal mucosa protein synthesis were determined. Highest liver protein synthesis rates were obtained with the diet compositions: lipid/carbohydrate ratio: 25 % lipids and 75 % carbohydrates (expressed as energy ratio). A higher proportion of lipids significantly decreases liver protein synthesis (p<0.05). Jejunal mucosa protein synthesis followed the same pattern, with the same statistical differences.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1997 Volume:46 | Number:3

Harvested from:

CDK

Metadata only:

false