This article presents a study of the state of vegetative balance and prognostic possibilities of quantitative parameters of functional activity of VNS to estimate a state of bodily adaptive reserves in children with severe BA. Bronchial asthma, being one of the most common chronic diseases in childhood, requires further research into predisposing and causally-significant factors, mechanisms of pathogenesis and peculiarities of a clinical course, improvement of methods of diagnostics, treatment, and prevention. Great importance in the development of bronchial asthma in children is given to genetically-fixed functional insufficiency of barrier tissues of the respiratory system, increased ability to synthesize allergic antibodies and produce certain cytokines, high bronchopulmonary sensitivity to mediators of allergic inflammation, lowered sensitivity of 3g-adrenoreceptors to endogenous catecholamins, changes in immunologic responsiveness, and disorder of neuroendocrinal regulation of immune responses. Implementation of genetic predisposition to bronchial asthma development is promoted by influence of adverse environmental factors., Hurmatoy Khankeldieva, Ibrohim Alimjanov, Habiba Negmatshaeva, Mavjuda Abdullaeva, Temur Tojiboev, Marifat Ganieva, and Literatura
Protection of reproductive health of adolescents and youth, i.e., individuals aged 15 to 24 years, is a primary goal of a family planning service as according to WHO estimations (1995), the youth aged 15 to 24 years makes over 14% of the overall population in developed countries. Disorders of a menstrual cycle take a leading place among gynaecologic pathologies of adolescent girls. At the same time, according to WHO data, about 30% of schoolchildren suffer from iron deficiency anemia, which takes one of the first places in the structure of somatic pathologies. On the basis of maternity welfare centre No. 2, 2,456 girls aged 15 to 18 years were examined, and the frequency of occurrence and structure of disorders of a menstrual cycle was studied. In addition to standard methods of examination, all patients undertook USI of small pelvis organs; indicators of a hormonal status, complete blood test, transport fund, and iron stocks were investigated. The study included 285 girls, with various disorders of a menstrual cycle, who had no history of iron deficiency states and exacerbation of chronic diseases. The control group included 69 adolescent girls with a regular menstrual cycle. The most common type of disorder of a menstrual cycle in subjects examined was dysmenorrhea I. Iron deficiency anaemia was found in 5.3% of the subjects examined. The frequency of occurrence of moderate anaemia and latent deficiency of iron of 46.7% and 11.9%, respectively, attracts our attention. Well-timed diagnostics of the states mentioned in adolescent girls can prevent subsequent development of reproductive and somatic pathologies., Ibragim Kasym-Hojaev, Gulnora Kamalova, Habiba Negmatshaeva, Hurmatoy Khankeldieva, and Literatura
Background: Obstetric complications developing at antiphospholipid syndrome are serious medical-social problem. Seeking of the treatment methods sets conditions for urgency of the article reviewed. Enzyme preparations are widely applied for treatment of women with fecundity disorder and hemorheology changes. Research objective was in clinico-laboratorial evaluation of Serrata drug impact in antiphospholipid syndrome in women with reproductive losses of Andijan state. Methods: Data of 43 women in the non-pregnancy state with reproductive losses (RL) in past history with revealed APS had been studied by us. Results: Thus, conducted therapy with Serrata was conductive to haemostasis. Conducted researches confirm the safety of application., Gulnoza Maniyozova, Habiba Negmatshaeva, Ozoda Yuldasheva, Gulnoza Turaeva, Dilfura Parpieva, and Literatura