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Start Over Creator Knížek, Jiří

1. Hmotnostní spektrometrie, některé trendy v současném biologickém výzkumu

Creator:
Knížek, Jiří, Půlpán, Zdeněk, Hubálek, Martin, Beránek, Ladislav, and Pokorný, Petr
Format:
print, bez média, and svazek
Type:
model:article and TEXT
Subject:
biofyzika, hmotnostní spektrometrie, biologický výzkum, biophysics, mass spectroscopy, biological research, 6, and 53
Language:
Czech
Description:
Příspěvek poskytuje přehlednou informaci o základních fyzikálních principech, na nichž pracují současné hmotnostní spektrometry, a informaci o základních principech některých důležitých soudobých hmotnostně spektrálních metod v biologickém výzkumu., Jiří Knížek, Zdeněk Půlpán, Martin Hubálek, Ladislav Beránek, Petr Pokorný., and Obsahuje seznam literatury
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Total HIP arthroplasty in patients with Parkinson's disease

Creator:
Pradeep, George Mathew, Šponer, Pavel, Kučera, Tomáš, Grinac, Michal, and Knížek, Jiří
Format:
print, text, and regular print
Type:
model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT
Subject:
staří, staří nad 80 let, náhrada kyčelního kloubu, kohortové studie, ženské pohlaví, nekróza hlavice femuru--komplikace--chirurgie, fraktury kyčle--komplikace--chirurgie, lidé, mužské pohlaví, Parkinsonova nemoc--komplikace--chirurgie, periprotetické fraktury--komplikace--chirurgie, selhání protézy, reoperace, and výsledek terapie
Language:
English
Description:
The aim of this study is to evaluate the results of total hip arthroplasty in patients with Parkinson's disease during a period of five years, focusing on the assessment of the risks and benefits of surgery. During this period we performed total hip arthroplasty in 14 patients (15 hips) with Parkinson's disease. Patients were evaluated by subjective symptoms and objective findings, with a focus on the use of support while walking and walking distance, severity of Parkinson's disease before surgery and at the time of the last follow-up. During the postoperative period, the following parameters were assessed: length of ICU stay, mobilization, complications, the total duration of hospitalization and follow-up care after discharge. Of the 11 patients (12 hips) followed-up 1-5 years with an average of 3 years after operation 8 cases showed progression of neurological disability. 5 patients (6 hips) showed an increased dependence on the use of support when walking and reduced distance that the patient was able to walk. Subjectively, 10 hip joints were completely painless and 2 patients complained of only occasional mild pain in the operated hip. Complications that were encountered were urinary tract infection (5 patients), cognitive impairment (3 patients) and pressure ulcer (2 patients). We did not observe any infection or dislocation of the prosthesis. Three patients fell and fractured the femur and 3 patients in our cohort died during follow up. Implantation of total replacement is possible with judicious indication after careful evaluation of neurological finding in patients with minimal or mild functional impairment of the locomotor system. Prerequisite for a good result is precise surgical technique and optimal implant position with balanced tension of the muscles and other soft tissues around the hip. and PG. Mathew, P. Sponer, T. Kucera, M. Grinac, J. Knízek
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public