Cadmium in the dose of 1 mg/animal/day was administered to guinea-pigs in the form of CdCl2 dissolved in drinking water during short-term (5 weeks) and subchronic (12 weeks) experiments. Both the control and cadmium-treated groups were divided into two subgroups, according to low (2 mg/animal/day) and high (100 mg/animal/day) vitamin C intake. Subchronic cadmium treatment caused copper deficiency indicated by a dramatic decrease of copper concentration in the liver and serum and by its moderate decrease in the testes and brain. Cadmium significantly increased zinc concentrations in the kidneys during the whole experiment and decreased the level of zinc in the serum after subchronic cadmium treatment. In the control groups, the levels of zinc and copper in the serum were lowered after 5 weeks of high vitamin C doses. High doses of vitamin C in cadmium-treated guinea-pigs decreased the levels of copper in the testes, brain and serum. These observations suggest that cadmium intake in relatively high doses might potentiate the development of copper deficiency, and high doses of vitamin C aggravate, to a certain extent, copper depletion in some important organs and serum of guinea-pigs.
Učebnicovou rolí žírných buněk je účast na alergických reakcích. Ukazují se ale být nezbytnými pro udržování integrity a funkce tkání, ovlivňují významně naši nervovou soustavu a zejména jsou klíčové pro minimalizaci účinků jedů. and The textbook role of mast cells is their participation in allergic reactions, but they also prove to be vital in preservation of tissue integrity and functions, they influence our nervous system and they are a key factor in minimizing the effects of animal venoms.
The project of restoration and preservation of the Bečov Castle, which received the Europa Nostra European Award in 2010, is described in another story. The project was awarded "for a thoroughly prepared conservation that would preserve the original architectonic element.' The educational part of the project offers a chance to see the development of architecture with concrete examples and the conservation methods applied to similar sights. and Marina Hužvárová, Gabriela Adámková a Markéta Pavlíková.