Na titanovém povrchu tvoří fibrinogen silněji adsorbovanou vrstvu s vyšší hustotou uspořádání v porovnání s porézní a slabě adsorbovanou vrstvou albuminu. Fibrinogen se lépe adsorbuje na povrch titanu upravený leštěním a leptáním nežli na povrch pouze leštěný. K silné adsorpci fibrinogenu dochází na povrchu titanu obohaceném v určitém poměru uhlíkem. Nejlépe se fibrinogen adsorboval na povrchu titanu pokrytém uhlovodíkovou vrstvou se složením Ti0,36 - C0,57 : H0,07 a Ti0,08 - C0,68 : H0,24. Takto upravený povrch titanu by tedy splňoval podmínky pro nejlepší oseointegraci. Adsorpce fibrinogenu na titanovou slitinu Ti6Al4V byla slabá, naopak silná byla na slitině TiNbTa, která má také dobré mechanické vlastnosti, pokud jde o výrobu implantátů. homopyrimidinové oligodeoxynukleotidy (ODN) tvoří na povrchu titanu robustnější vrstvy s vyšší hustotou v porovnání se stejně dlouhými homopurinovými ODN a velice porézními vrstvami dvoušroubovicových fragmentů DNA., Fibrinogen is absorded at the titanium surface more firmly and with higher density contrary to a weakly adsorbed and porous albumin layer. Fibrinogen is better absorbed at the titanium surface treated by polishing and etching than at the surface treated only by polishing. Fibrinogen is strongly adsorbed at the titanium layer enriched by carbon to a certain ratio. The best adsorption of fibrinogen was observed at the titanium surface enriched with carbon at the ratio Ti0,36 - C0,57 : H0,07 a Ti0,08 - C0,68 : H0,24. The titanium surface treated in this way should fulfill the conditions for the best oseointegration. Adsorption of fibrinogen at the titanium alloy T6Al4V was weak contrary to the good adsorption at the TiNbTa alloy, which also has good mechanical properties concerning implant production. Homopyrimidine oligodeosynucleotides (ODN) form at the titanium surface more robust layers with higher density contrary to the homopurine ODN molecules of the same length and very porous layers of double stranded DNA fragments., Vladimír Vetterl, Stanislav Hasoň, Raimo Silvennoinen, Ladislav Cvrček, Luděk Strašák, Lukáš Fojt., and Obsahuje bibliografii
INTRODUCTION: The aim of this study was to find out the impact of degradation and regeneration of force over time at NiTi springs on the value and course of the final acting force and to verify the possibility of using these phenomena for a directed transition to the reverse plateau and its maintaining. METHODS: Static and cyclic mechanical loadings were performed. At first unused springs were tested. Afterwards the springs were mechanically stabilized by stress cycling and finally tested again. The difference in shape of the working curves was assessed. For simulation and description of the force degradation the modified Voight model was used. RESULTS: New springs, mainly those with large hysteresis, showed a significant stress-strain curve movement and shape changes during the cycling. The effect of the stress-strain curve course change disappeared fully in the stabilized springs. Multiple loading led to an overall decrease of force value during the measurement. The effect of force degradation and regeneration over time by simple static loading varies in the range of percentage of the nominal force in the plateau area. The transition between stress-strain curve phases caused by the degradation or regeneration of the force wasn't observed in case of mechanically stabilized springs. CONCLUSIONS: Springs should be mechanically stabilized before their application. The degree of force degradation over time is insignificant for mechanically stabilized springs. Degradation or regeneration of force over time, mechanical stabilization or micromovements in the mouth don't cause any transition between individual stress-strain curve phases. and A. Bezrouk, L. Balský, M. Smutný, T. Nosek, J. Záhora, J. Hanus, R. Polma