The final conference of project ProAct, a Coordination Action financed within the Regions of Knowledge activity of the European Commission, took place on 20th of September 2007 in Prague. In ProAct, four old and four new EU member states join forces in search of the best innovation of regional innovation policy implementation. The key factors of success in the South Moravian Region in the Czech Republic are political commitment, funding and appropriate regional conditions. The regional weaknesses are the lack of skilled people for business development support. and Jiří Loudín.