This is an experimental study of lung morphology in modeling sepsis on a background of severe purulentinflammatory disease of soft tissues (necrotizing fasciitis) by original authors' method. The study showed that early stages of sepsis (13 days) were characterized by manifestations of changes in lung tissue as vascular response, in the second period (the 7th day) by appearance and growth of nonobstructive microatelectases, whereas the third period (the 14th day) was characterized by progression of purulentnecrotic processes in soft tissues, development of surgical sepsis and acute respiratory distress syndrome. These changes in morphological structure of lung tissue are specific for generalized septic process and consequences of necrotizing fasciitis with its septic complication., Yorkin Azizov, Alisher Ohunov, and Literatura