Intracellular free Ca2+ is one of important biological signals regulating a number of cell functions. It has been discussed widely and extensively in several cell types during the past two decades. Attention has been paid to the Ca2+ transportation in mesenchymal stem cells in recent years as mesenchymal stem cells have gained considerable interest due to their potential for cell replacement therapy and tissue engineering. In this paper, roles of intracellular Ca2+ oscillations and its transporters in mesenchymal stem cells have been reviewed., B. Ye., and Obsahuje bibliografii a bibliografické odkazy
Circadian and circaannual oscillations of tissue lipid peroxides (LPO) were studied in young male Wistar rats. The concentration of malondialdehyde, one of LPO degradation products, was measured at 3-h intervals during 24 hours in rats, adapted to lightrdark 12:12 h regimen in the course of the year. LPO in the liver, thymus and bone marrow oscillated rhythmically in the course of the day and year. Circadian oscillations in all tissues were two-peaked, with zeniths at various times of the light and dark parts of the day. In the liver and thymus, the highest mesors were found during the winter, in the bone marrow during the spring. The same holds for amplitude values, with the exception of the bone marrow which exhibited the highest values during the summer. The reason for the LPO oscillations is probably resulting from the changing ratio of pro- and anti-oxidative capacities in various tissues during the day and the year.
We studied the circadian oscillation of lipid peroxides (TBARS) in the pineal gland of rats adapted to light:dark 12:12 h regimen. The concentration of TBARS was determined at 3-h intervals during 24 hours. TBARS of pineal gland oscillated rhytmically during the 24 h period. The maximal concentration of lipoperoxidative products was found at 20.00 h and 02.00 h and the lowest values at 08.00 h and 23.00 h. The determination of antioxidant capacity is needed for explaining the mechanism of TBARS oscillations in the pineal gland.
We review the basic features of oscillations observed at different height levels in the sunspot atmosphere, moreover, various possibilities for a theoretical interpretation are discussed. In the umbra oscillation power is concentrated in severa] period bands
(3 min., 5 min., and ≥ 20 min.) which on their part are composed of closely packed peaks. The observed amplitudes and phases of velocity and of intensity oscillations depend in a characteristic way on the period and on the height. These features are used to look for the most probable physical mechanisms which could produce the different modes: At subphotospheric depths two independent resonators are acting. A resonator for slow, quasi-transveree waves can explain the lifetimes of umbral dots (≥ 20 min.), while a resonator for fast (acoustic), quasi-longitudinal waves could result in the umbral 5-min. oscillations. The acoustic resonator strongly couples with the slow-mode longitudinal resonator at photospheric and chromospheric heights, the latter produces the resonance peaks in the 3-min. band. Running penumbral waves can be explained by the transformation of 5-min, waves from the convective zone in the almost horizontal magnetic field. The interpretation of oscillations provides a new method of probing not only subphotospheric, but also atmospheric layers of sunspots (e.g., of determining temperature gradients), thus completing customary spectroscopic diagnostics.