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Start Over Subject morris water maze

1. Application of computer-controlled, real-time TV single-object tracking in behavioural biology and rehabilitation medicine

Creator:
Kaminsky, Yu. and Krekule, I.
Type:
article, model:article, and TEXT
Subject:
TV tracking, PC, TV, morris water maze, and real-time imaging
Language:
English
Description:
A PC-based system with TV input for automatic tracking of a single and contrast object in 2D in a homogeneous and stationary environment has been developed and applied to Morris water maze experiments. Further development of the system aimed at broader support of experiments, reduction of requirements on the stationarity and homogeneity of the scene background and on multiple-object tracking is discussed. The computer control of active light markers of the tracked object applicable to multiple-objects tracking in a time-sharing regime is also mentioned in the conclusion. The latter extension of the system can be applied to kinematic studies in biomechanics, sport and rehabilitation medicine.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Disturbance of the magnetic field did not affect spatial memory

Creator:
Li, Y., Zhang, C., and Song, T.
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, učení, paměť, learning, memory, ELF-MF, previous training, morris water maze, 14, and 612
Language:
English
Description:
Extremely low-frequency magnetic field (ELF-MF) has been suggested to influence the cognitive capability but this should be dynamically evaluated in a longitudinal study. Previous training can affect performance, but the influence under magnetic field is unclear. This study aims to evaluate the effects of previous training and ELF-MF exposure on learning and memory using the Morris water maze (MWM). Sprague-Dawley rats were subjected to MWM training, ELF-MF exposure (50 Hz, 100 μT), or ELF-MF exposure combined with MWM training for 90 days. Normal rats were used as controls. The MWM was used to test. The data show that the rats exposed to training and ELF-MF with training performed better on spatial acquisition when re-tested. However, during the probe trial the rats showed no change between the training phase and the test phase. Compared with the control group, the ELF-MF group showed no significant differences. These results confirm that previous training can improve the learning and memory capabilities regarding spatial acquisition in the MWM and this effect can last for at least 90 days. However, this improvement in learning and memory capabilities was not observed during the probe trial. Furthermore, ELF-MF exposure did not interfere with the improvement in learning and memory capabilities., Y. Li, C. Zhang, T. Song., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

3. Long-term results of enriched environment and erythropoietin after hypobaric hypoxia in rats

Creator:
Hralová, M., Yvona Angerová, Tereza Gueye, Jana Bortelová, Olga Švestková, Tomáš Zima, and Marcela Lippertová-Grünerová
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, global cerebral hypoxia, enriched environment, erythropoietin, morris water maze, spatial memory, 14, and 612
Language:
English
Description:
After global cerebral hypoxia, many patients are severely disabled even after intensive neurorehabilitation. Secondary mechanisms of brain injury as a result of biochemical and physiological events occur within a period of hours to months, and provide a window of opportunity for therapeutic intervention. Erythropoietin (EPO) has been shown to be neuroprotective in the brain subjected to a variety of injuries. Fifty-nine 3-month-old male Wistar rats were randomly distributed to experimental groups with respect to the housing (enriched environment – EE, standard housing – SH), to hypoxia exposure, and to EPO treatment. An acute mountain sickness model was used as a hypobaric hypoxia simulating an altitude of 8000 m. One half of the animals received erythropoietin injections, while the others were injected saline. Spatial memory was tested in a Morris water maze (MWM). The escape latency and the path length were measured. Better spatial learning in MWM was only seen in the group that received erythropoietin together with enriched environment. EPO administration itself had no influence on spatial memory. The results were very similar for both latencies and path lengths. These results support the idea that after brain injuries, the recovery can be potentiated by EPO administration combined with neurorehabilitation., M. Hralová, ... [et al.]., and Obsahuje seznam literatury
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

4. Sex differences in ICR mice in the morris water maze task

Creator:
Ge, J.-F., Qi, C.-C., Qiao, J.-P., Wang, C.-W., and Zhou, J.-N.
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, sex, learning behavior, memory, mouse, morris water maze, 14, and 612
Language:
English
Description:
The Morris water maze (MWM) is one of the most common tasks used to assess spatial learning and memory ability in rodents. Genetic strain and gender are two prominent variants that influence spatial performance. Although it was reported that ICR (Institute of Cancer Research) mice exhibited an unchanged baseline performance in the training phase of the MWM task, this outbred strain has been widely used in learning and memory studies, and little is known regarding the effects of sex on behavioral performance. In this study, we demonstrated that both male and female ICR mice could complete the MWM task. Furthermore, a significant sex difference was observed, with females having shorter escape latencies and longer durations in the target quadrant in both the acquisition and test phases. Our findings emphasize the necessity of careful examination of not only the strain effect on behavioral performance but also the sex effect., J.-F. Ge, ... [et al.]., and Obsahuje seznam literatury
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public