Search

Start Over Subject iodine

1. A modified method for clearing, staining and mounting plant-inhabiting mites

Creator:
Faraji, Farid and Bakker, Frank
Type:
article, model:article, and TEXT
Subject:
Acari, iodine, staining, and microscope slides
Language:
English
Description:
A modified method for clearing, staining and mounting plant-inhabiting mites is proposed. With this method, all mites can be cleared with a single agent and mounted in a single medium. The stain added to the mounting medium enhances the clarity of the fine structures of soft-bodied mites under phase contrast and more significantly under bright field microscopy.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

2. Antiviral activity of amiodarone in SARS-CoV-2 disease

Creator:
Bílek, Radovan, Danzig, Vilém, and Grimmichová, Tereza
Format:
počítač and online zdroj
Type:
model:article and TEXT
Subject:
amiodarone, iodine, SARS-CoV-2, COVID-19, and antiviral activity
Language:
English
Description:
Amiodarone seems to exhibit some antiviral activity in the disease caused by SARS-CoV-2. Here we have examined the SARS-CoV-2 disease course in the entire population of the Czech Republic and compared it with the course of the disease in patients treated with amiodarone in two major Prague’s hospitals. In the whole population of the Czech Republic SARSCoV-2 infected 1665070 persons (15.6 %) out of 10694000 (100 %) between 1 April 2020 and 30 June 2021. In the same time period only 35 patients (3.4 %) treated with amiodarone were infected with SARS-CoV-2 virus out of 1032 patients (100 %) who received amiodarone. It appears that amiodarone can prevent SARS-CoV-2 virus infection by multiple mechanisms. In in-vitro experiments it exhibits SARS-CoV-2 virus replication inhibitions. Due to its anti-inflammatory and antioxidant properties, it may have beneficial effect on the complications caused by SARS-CoV-2 as well. Additionally, inorganic iodine released from amiodarone can be converted to hypoiodite (IO- ), which has antiviral and antibacterial activity, and thus can affect the life cycle of the virus.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

3. Iodine, thyroglobulin and thyroid gland

Creator:
Bílek, Radovan, Dvořáková, Marcela, Grimmichová, Tereza, and Jiskra, Jan
Format:
počítač and online zdroj
Type:
model:article and TEXT
Subject:
jod, moč, štítná žláza, iodine, urine, thyroid gland, thyroglobulin, serum, 14, and 612
Language:
English
Description:
Iodine is essential in the biosynthesis of thyroid hormones that affect metabolic processes in the organism from the prenatal state to the elderly. The immediate indicator of iodine intake is the concentration of iodine in urine, but the indicator of iodine intake in the longer term of several months is thyroglobulin (Tg). Tg negatively correlated with increasing intake of iodine in population that do not suffer from thyroid disease, while a more than adequate to excessive iodine intake leads to an increase in Tg. The dependence of Tg on iodine can be described by a U-shaped curve. Thyroglobulin in serum is elevated in thyroid disease mainly in hyperthyroidism (diagnosis E05 of WHO ICD-10 codes) and in goiter (diagnosis E04 of WHO ICD-10 codes). Tg values decrease below 20 µg/l after effective treatment of patients with thyroid disease. Thyroglobulin may thus be an indicator of thyroid stabilization and the success of the thyroid gland treatment., Radovan Bílek, Marcela Dvořáková, Tereza Grimmichová, Jan Jiskra., and Obsahuje bibliografii
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

4. The relationship between iodine intake and serum thyroglobulin in the general population

Creator:
Radovan Bílek, Jarmila Čeřovská, and Václav Zamrazil
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, jod, toleranční meze, iodine, tolerance limits, thyroglobulin, population studies, normal individuals, 14, and 612
Language:
English
Description:
The relationship is shown between a concentration of urinary iodine and serum thyroglobulin in population studies carried out on a general population that was randomly selected from the registry of the General Health Insurance Company (individuals aged 6-98 years, 1751 males, 2420 females). The individuals were divided into subgroups with a urinary iodine concentration of <50, 50-99, 100-199, 200-299 and ≥300 μg/l. The mean and median of thyroglobulin were calculated in these subgroups. Tg concentrations were dependent on gender (males<females), age (thyroglobulin increased with age) and statistically significant negative relationship was observed between thyroglobulin and urinary iodine in individuals with urinary iodine <300 μg/l and the age under 65 years. Upper nonparametric tolerance limits of thyroglobulin in relation to iodine intake were calculated in subgroup of normal individuals (n=1858, thyroglobulin, urinary iodine, thyrotropin and free thyroxine were within the normal reference range). Upper limits were dependent on gender and age. The total value of upper limits is 44 μg/l; for individuals aged 6-17 years it is 39.1 μg/l; 18-65 years = 51.4 μg/l and 66-98 years = 60.6 μg/l. In general, thyroglobulin serum concentrations higher than 40 μg/l should be an indicator for determining urinary iodine., R. Bílek, J. Čeřovská, V. Zamrazil., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public