Gaits is one of the splendid functions, which concerns every human being. The standard gait is perceived as precisely controlled activities, based on the periodically coordinated, recurrent leg and trunk (torso) movements, which provide the relocation of the human body from one place to another with the minimal waste energy (Gage J.R., DeLuca P.A., Renshaw T.S. - gait definition) [2]. Different types of diseases cause the changes in gait pattern of the parients. The patients, who have the certain diseases since they were born and the acquired diseases have different deviations from the gait pattern. The conclusion is that there is no universal gait pattern.
The gait of the patients with implants differs from the gait pattern and in this case it depends on the implants type. Analysis and estimation of the gait of the people who have implants is problematic, that is why the paper presents the research connected with the gait diagnostics for people with implants.
This comparative study of various surface treatments of commercially available implant materials is intended as guidance for orientation among particular surface treatment methods in term of the cell reaction of normal human osteoblasts and blood coagulation. The influence of physicochemical surface parameters such as roughness, surface free energy and wettability on the response of human osteoblasts in the immediate vicinity of implants and on the blood co agulation was studied. The osteoblast proliferation was monitored and the expression of tissue mediators (TNF-α , IL-8, MMP-1, bone alkaline phosphatase, VCAM-1, TGF-β ) was evaluated after the cell cultivation onto a wide range of commercially available materials (titanium and Ti6Al4V alloy with various surface treatments, CrCoMo alloy, zirconium oxide ceramics, polyethylene and carbon/carbon composite). The formation of a blood clot was investigated on the samples immersed in a freshly drawn whole rabbit blood using scanning electron microscope. The surfaces with an increased osteoblast proliferation exhibited particularly higher surface roughness (here Ra > 3.5 μm) followed by a high polar part of the surface free energy whereas the effect of wettability played a minor role. The surface roughness was also the main factor regulating the blood coagulation. The blood clot formation analys is showed a rapid coag ulum formation on the rough titanium-based surfaces. The titanium with an etching treatment was considered as th e most suitable candidate for healing into the bone tissue due to high osteoblast proliferation, the highest production of osteogenesis markers and low production of inflammatory cytokines and due to the most intensive blood clot formation., D. Kubies ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy