The administration of a diet containing 5 % of dried oyster mushroom to male Wistar rats fed a cholesterol diet (0.3 %) shortly after weaning for 8 weeks reduced cholesterol levels in the serum and liver by 27 and 33 %, respectively and increased the fractional turnover rate of 125l-very-low-density lipoproteins (VLDL) by more than 30 %.