This paper presents the results of an experimental and numerical study of a vertical slot fishway (VSF). A 2-D depth-averaged shallow water numerical model PCFLOW2D coupled with three different turbulent models (constant eddy viscosity, Smagorinsky and k - ε) was used. A detailed analysis of numerical parameters needed for a correct simulation of the phenomenon was carried out. Besides the velocity field, attention was paid to important hydraulic parameters such as maximum velocity in the slot region and energy dissipation rate ε in order to evaluate the performance of VSF. A scaled physical hydraulic model was built to ensure reliable experimental data for the validation of the numerical model. Simulations of variant configurations of VSF showed that even small changes in geometry can produce more fishfriendly flow characteristics in pools. The present study indicates that the PCFLOW2D program is an appropriate tool to meet the main demands of the VSF design.