This article is devoted to issues concerning database processing of the correspondence of Bedřich Smetana, as the fundamental starting point for a plan to make this correspondence accessible in book form, in a traditional critical edition. The Association for Central European Cultural Studies in Prague has been developing a database information system for the editors since 2006. The author outlines the basic methodological issues (maximally-abstracted information as the basic unit of a multifunctional database system, structuring and building of this system based on the principle of interconnected modules, its openness to incorporation of data in various formats, etc.), then summarizes the benefits of such an on-line running database for editors intending to publish the results of their work as an edition in book form (variability of print outputs with the possibility of publishing statistically-processed data in the form of tables and graphs, incorporation of textual analyses of correspondence into specially-structured modules and subsequent use thereof in generating various types of indices for the printed edition). Finally, he considers the possibility of transforming the application into an autonomous system accessible on the internet, providing up-to-date information about Smetana’s epistolary bequest.