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2. Global brain dynamics of transient visual evoked potentials
- Creator:
- Kremláček, J. and Miroslav Kuba
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, zrakové evokované potenciály, visual evoked potentials, visual motion stimulation, independent component analysis, motion processing, 14, and 612
- Language:
- English
- Description:
- J. Kremláček, M. Kuba. and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
3. Model of Visually Evoked Cortical Potentials
- Creator:
- Kremláček, J., Kuba, M., and Holčík, J.
- Format:
- print, bez média, and svazek
- Type:
- article, studie, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, Mathematical model, Visual evoked potentials, Pattern-reversal, Motion-onset, 14, and 612
- Language:
- English
- Description:
- The pattern-reversal (P-VEPs) and the motion-onset (M-VEPs) of visual evoked potentials were modeled by means of three damped oscillators (O1, O2, O3) of identical construction. The O1, assumed to simulate the response of primary visual area (V1), was driven by the firing density of the lateral geniculate nuclei. O1 contributed mainly to the N75 and P100 peaks of the P-VEPs. The O2, driven by the O1 output, mimics the activity of V2, V3a, and MT. It contributed to the negative peak N145 of the P-VEPs or to the N160 in the M-VEPs. The O3 was suggested to model late slow processes probably of an attentive origin. The model parameters were set by optimization to follow the P-VEPs and M-VEPs obtained as a grand average of four young volunteers (PZ - A2 lead). The evoked potentials were described with normalized root mean square error lower than 13 %., J. Kremláček, M. Kuba, J. Holčík., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
4. Serum levels of aryl hydrocarbon receptor, cytochromes P450 1A1 and 1B1 in patients with exacerbated psoriasis vulgaris
- Creator:
- Beránek, M., Fiala, Z., Kremláček, J., Andrýs, C., Krejsek, J., Hamáková, K., Palička, V., and Borská, L.
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- aryl hydrocarbon receptor, psoriasis, cytochrome P450, CYP1A1, CYP1B1, Goeckerman therapy, and crude coal tar
- Language:
- English
- Description:
- The aryl hydrocarbon receptor (AhR) is highly expressed in psoriasis skin lesions. The aim of this study was to investigate serum concentrations of AhR, cytochromes P450 (CYP) 1A1 and 1B1 in patients with exacerbated psoriasis vulgaris treated with combined therapy of ultraviolet radiation (UVR) and crude coal tar. The analyses were performed by using enzyme-linked immunosorbent assays. Before the treatment, the patients had significantly higher serum levels of AhR and CYP1A1 than healthy controls. AhR median noticeably decreased after the therapy; nevertheless, it remained significantly higher compared to the controls. CYP1A1 levels measured before and after the therapy did not differ significantly. Serum CYP1A1 positively correlated with AhR values before and after the treatment. The serum values of CYP1B1 were very low and we did not see any differences between the study group and the control group. The study demonstrated that serum levels of AhR and CYP1A1 could indicate their immunopathological and metabolic roles in exacerbated psoriasis. and Corresponding author: Martin Beránek
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public