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Start Over Contributor Čelakovský, Petr , 1966-

1. Detection of cervical lymph node micrometastases in patients with squamous cell carcinoma of the oral cavity, pharynx and larynx

Creator:
Čelakovský, Petr, Kalfeřt, David, Smatanová, Katarína, Chrobok, Viktor, and Laco, Josef
Format:
print, text, and regular print
Type:
model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT
Subject:
spinocelulární karcinom--patologie--chirurgie, ženské pohlaví, lidé, nádory hrtanu--patologie--chirurgie, lymfadenektomie--metody, mužské pohlaví, lidé středního věku, nádory úst--patologie--chirurgie, disekce krku--metody, mikrometastázy--diagnóza--patologie, staging nádorů, péče o pacienty - plánování, nádory hltanu--patologie--chirurgie, prediktivní hodnota testů, prognóza, prospektivní studie, and reprodukovatelnost výsledků
Language:
English
Description:
BACKGROUND: The goal of this prospective study was to determine the frequency of micrometastases in patients with squamous cell carcinoma (SCC) of the oral cavity, pharynx and larynx in whom elective neck dissection was indicated (cN0). PATIENTS AND METHODS: A total of 12 patients (10 males and 2 females) were enrolled in the study. The age ranged 42-73 years (median 62 years). Elective neck dissection was performed in all patients (8 ipsilateral, 4 bilateral) and a total of 256 lymph nodes were removed and sent for microscopic examination. RESULTS: The presence of tumor cells in cervical lymph nodes was found in 5/12 (42%) patients. Micrometastases of SCC were found in two patients and isolated tumor cells (ITC) in two other patients. In the remaining one patient with oropharyngeal SCC, a micrometastasis of papillary thyroid carcinoma (PTC) was detected. Positive lymph nodes were localized in level II in three patients with SCC of larynx, hypopharynx and tongue base, respectively, in level I in one patient with SCC of oral tongue and in level III in one patient with PTC. CONCLUSION: Our results indicate that SCC of head and neck has a high potential for creating micrometastases which frequency is higher compared to clinically detected macrometastases. Therefore, elective neck dissection or radiotherapy of the neck should be considered in patients with high risk of occult metastases or micrometastases. and P. Čelakovský, D. Kalfeřt, K. Smatanová, V. Chrobok, J. Laco
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

2. Oncocytic Schneiderian papilloma of frontal sinus

Creator:
Kalfeřt, David, Laco, Jan, Čelakovský, Petr, Smatanová, Katarína, and Ludvíková, Marie
Format:
print, text, and regular print
Type:
model:article, article, Text, kazuistiky, časopisecké články, práce podpořená grantem, and TEXT
Subject:
biopsie, diferenciální diagnóza, ženské pohlaví, sinus frontalis, lidé, lidé středního věku, otorinolaryngologické chirurgické výkony--metody, papilom--diagnóza--chirurgie, nádory vedlejších dutin nosních--diagnóza--chirurgie, and počítačová rentgenová tomografie
Language:
English
Description:
Oncocytic Schneiderian papilloma (OSP) is one of the three morphologically distinct tumors that arise from Schneiderian membrane (the others include exophytic papilloma and inverted papilloma). OSP almost always occurs unilaterally in the paranasal sinuses, usually in the maxillary sinus, ethmoid cells or sphenoid sinus. We report a case of a 64-year-old woman with OSP arising from the left frontal sinus. In the report herein, we describe an OSP originating in the region of frontal sinus, which, to the best of our knowledge, represents the first documented example in English literature of OSP developing in this anatomical site. and D. Kalfert, J. Laco, P. Celakovský, K. Smatanová, M. Ludvíková
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public