Contribution to the V-V interval optimizaton in patients with cardiac resynchronization therapy

Title:

Contribution to the V-V interval optimizaton in patients with cardiac resynchronization therapy

Creator:

Miroslav Novák, Jolana Lipoldová, Jaroslav Meluzín, Krejčí, J., Petr Hude, Věra Feitová, Ladislav Dušek, Pavel Kamarýt, and Jiří Vítovec

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:f4ba5ac7-df5f-483f-b01f-243618023e75
uuid:f4ba5ac7-df5f-483f-b01f-243618023e75
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, kardiologie, angiologie, cardiology, angiology, biventricular pacing, inter-ventricular asynchrony, intra-ventricular asynchrony, V-V interval, cardic resynchronization therapy, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The present study proposed procedure for predicting an optimal left and right ventricular pacing interval delay (V-V interval). In 16 patients (heart failure, left bundle branch block, biventricular pacing) two methods (A and B) identifying optimal V-V interval were tested. Method A: predicted optimal V-V interval A (POVV-A) = electromechanical delay of the segment paced by left ventricle lead minus electromechanical delay of the segment paced by right ventricle lead. Method B: predicted optimal V-V interval B (POVV-B) = difference in the onset of aortic and pulmonary flows. Both methods were validated using echocardiography and right-sided heart catheterization. Cardiac output during POVV-A (4.6 l.min-1 ) was significantly better than that during POVV-A minus 20 ms (4.3 l.min-1, p<0.01) and POVV-A plus 20 ms (4.3 l.min-1 , p<0.01), and than that during POVV-B (4.4 l.min-1, p<0.05). LV dP/dt during POVV-A (818 mm Hg.s-1 ) exceeded that during POVV-A plus 20 ms (717 mm Hg.s-1 , p<0.05) and POVV-A minus 20 ms (681 mm Hg.s-1, p<0.05), and that during POVV-B (727 mm Hg.s-1 , p<0.01). The time difference in onsets of myocardial deformation of left ventricle segment paced by the left ventricle and right ventricle lead allows identifying the optimal V-V interval and improves left ventricle performance., M. Novák, J. Lipoldová, J. Meluzín, J. Krejčí, P. Hude, V. Feitová, L. Dušek, P. Kamarýt, J. Vítovec., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2008 Volume:57 | Number:5

Harvested from:

CDK

Metadata only:

false