Dependence of QT interval on the heart rate during alterations of pulmonary ventilation in young healthy subjects

Title:

Dependence of QT interval on the heart rate during alterations of pulmonary ventilation in young healthy subjects

Creator:

Kujaník, Š., Valachová, A., Kubáček, L., and Mikulecký, M.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:db69888c-74f1-4123-8895-0ff1ac705be6
uuid:db69888c-74f1-4123-8895-0ff1ac705be6

Subject:

QT interval, hyperventilation, hypoxia, valsalva manoeuvre, electrocardiography, and vectorcardiography

Type:

article, model:article, and TEXT

Description:

In 77 young healthy volunteers of both sexes the dependence of the QT interval of ECG on the heart rate was investigated during normal ventilation (control) and after 1, 2, 3, 4 min of voluntary hyperventilation, after 6 min of hypoxic-hypercapnic ventilation (through an enlarged dead space) and during the Valsalva manoeuvre. The absolute coefficients (a) of the regression lines QT = a + b . HR were significantly different in all groups. The slopes of regression lines (b) were significantly different in all groups with the exception of 4 min hyperventilation. Our results indicate that short-term alterations of pulmonary ventilation may change not only the duration of the QT interval but also its dependence on the heart rate. Voluntary hyperventilation lasting 1-2 min and the Valsalva manoeuvre decrease the rate dependence of the QT interval and this change may cause its prolongation at higher heart rates.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1993 Volume:42 | Number:6

Harvested from:

CDK

Metadata only:

false