The origin of 7α-hydroxy-dehydroepiandrosterone and its physiological role: a history of discoveries

Title:

The origin of 7α-hydroxy-dehydroepiandrosterone and its physiological role: a history of discoveries

Creator:

Luboslav Stárka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:da2de455-a050-4885-b1a5-65f2732ac72b
uuid:da2de455-a050-4885-b1a5-65f2732ac72b
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, 11β-hydroxysteroid dehydrogenase, CYP7B, immunomodulatory effects, occurrence, dehydroepiandrosterone, 7α-hydroxy-dehydroepiandrosterone, neurosteroid, 14, and 612

Type:

article, články, journal articles, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Nearly 60 years has elapsed since the first isolation and identification of 7α-hydroxy-dehydroepiandrosterone, and in that time much information has been gained on its occurrence, metabolism, ontogeny, immunomodulatory activity, cell proliferation, cortisol control in local tissues and neuroactivity. Additional knowledge about this steroid may elucidate its role in obesity, neurodegenerative disturbances such as Alzheimer’s disease, or psychiatric disorders such as schizophrenia or depression. This review aims to provide a comprehensive summary of the available literature on 7α-hydroxydehydroepiandrosterone., L. Stárka., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2017 Volume:66 | Number:Suppl 3

Harvested from:

CDK

Metadata only:

false