Differences in enterocyte brush border enzyme activities in ageing rats reared in germ-free and conventional conditions

Title:

Differences in enterocyte brush border enzyme activities in ageing rats reared in germ-free and conventional conditions

Creator:

Kozáková, H., Štěpánková, R., Řeháková, Z., and Kolínská, J.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:caab2e4b-2c33-448f-b01e-c199b7a0b793
uuid:caab2e4b-2c33-448f-b01e-c199b7a0b793

Subject:

enterocytes, lactase, sucrase, glucoamylase, and dipeptidyl peptidase IV

Type:

article, model:article, and TEXT

Description:

The aim of this study was to evaluate the levels of disaccharidase and dipeptidyl peptidase IV activities in rat jejunal enterocytes under the influence of long-term germ-free conditions. We found that the brush-border lactase and dipeptidyl peptidase IV activities were two to three times higher in 2-month-old germ-free rats in comparison with their conventional counterparts. The highest effect of germ-free condition was observed on lactase activity in 6-month-old and dipeptidyl peptidase IV in 2-month-old rats. No difference between germ-free and conventional rats in sucrase and glucoamylase activities was found in 2-month-old rats. The difference develops with increasing age, sucrase activity becoming significantly higher in 6- and 12-month-old rats and glucoamylase in 12-month-old germ-free rats.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1998 Volume:47 | Number:4

Harvested from:

CDK

Metadata only:

false