The role of pulmonary artery wedge pressure on the incidence of atrial fibrillation and atrial tachycardias in patients with isolated pre-capillary pulmonary hypertension

Title:

The role of pulmonary artery wedge pressure on the incidence of atrial fibrillation and atrial tachycardias in patients with isolated pre-capillary pulmonary hypertension

Creator:

Dusik, Milan, Fingrova, Zdenka, Ambroz, David, Jansa, Pavel, Linhart, Ales, and Havranek, Stepan

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:c51fd30f-3c3c-4641-9397-c8b016d824bc
uuid:c51fd30f-3c3c-4641-9397-c8b016d824bc
doi:10.33549/physiolres.934706

Subject:

pulmonary hypertension, atrial fibrillation, atrial tachycardia, atrial flutter, and pulmonary artery wedge pressure

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

Atrial fibrillation and atrial tachycardias (AF/AT) have been reported as a common condition in patients with pulmonary hypertension (PH). As yet, limited data exists about the significance of the borderline post-capillary pressure component on the occurrence of AF / AT in patients with isolated pre-capillary PH. We retrospectively studied the prevalence of AF / AT in 333 patients (mean age 61±15 years, 44 % males) with pre-capillary idiopathic / familiar pulmonary arterial hypertension, and inoperable chronic thromboembolic pulmonary hypertension. The prevalence of AF / AT was analyzed in different categories of pulmonary artery wedge pressure (PAWP). In the study population overall, the mean PAWP was 10.5±3 mmHg, median of 11 mmHg, range 2-15 mmHg. AF / AT was diagnosed in 79 patients (24 %). The proportion of AF / AT among patients with PAWP below the median (≤11 mmHg) was lower than in subjects with PAWP between 12 and 15 mmHg, 30 (16 %) vs. 46 (35 %), p=0.0001. Compared to the patients with PAWP≤11 mmHg, subjects with PAWP between 12 and 15 mmHg were older (65±13 years vs. 58±16), with more prevalent arterial hypertension [100 (70 %) vs. 106 (55 %)] and diabetes mellitus [50 (35 %) vs. 48 (25 %)], showed larger size of the left atrium (42±7 vs. 40±6 mm), and higher values of right atrium pressure (12±5 vs. 8±5 mmHg), p<0.05 in all comparisons. The prevalence of AF / AT in the group studied increased with the growing post-capillary component.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

841-849

Source:

Physiological research | 2021 Volume:70 | Number:6

Harvested from:

CDK

Metadata only:

false