Histological changes of the middle ear ossicles harvested during cholesteatoma surgery

Title:

Histological changes of the middle ear ossicles harvested during cholesteatoma surgery
Histological changes of the middle ear ossicles harvested during cholesteatoma surgery

Creator:

Školoudík, Lukáš, Šimáková, Eva, Kalfeřt, David, and Chrobok, Viktor

Contributor:

Školoudík, Lukáš, Šimáková, Eva, Kalfeřt, David, and Chrobok, Viktor , 1964-

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bmc16019681-6abe3b2b-e0d4-41bc-81d5-b821a9e70711
uuid:bmc16019681-6abe3b2b-e0d4-41bc-81d5-b821a9e70711
local:bmc16019681
http://actamedica.lfhk.cuni.cz/
doi: 10.14712/18059694.2016.2
local: bmc16019681

Subject:

mladiství, dospělí, staří, dítě, předškolní dítě, cholesteatom středního ucha--patologie--chirurgie, kohortové studie, sluchové kůstky--patologie, epitelové buňky--patologie, ženské pohlaví, lidé, inkus--patologie, mužské pohlaví, malleus--patologie, lidé středního věku, transplantace autologní, and mladý dospělý

Type:

model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT

Format:

print, text, and regular print

Description:

BACKGROUND: In the cholesteatoma surgery ossicles can be replaced to reconstruct middle ear function. It is important that these ossicles are free of squamous epithelium, to prevent residual disease. This study focuses on the histological findings of the malleus and incus harvested during cholesteatoma surgery. MATERIALS AND METHODS: Eighty middle ears ossicles were examined in vivo and histologically to consider the relationship of cholesteatoma to ossicles, grade of bone destruction and invasion of cholesteatoma to deeper layers of bone. RESULTS: Serious ossicular destruction was observed more frequently in incus compared to malleus (p=0.0065). Difference of ossicles destruction between children and adults was not significant (p=0.3032). Deep invasion of cholesteatoma into the vascular spaces or inner core of the bone was not observed. CONCLUSIONS: Autograft ossicles from cholesteatomatous ears should not necessarily be rejected for reconstruction of the ossicular chain. Regarding the histological finding, the authors suggest mechanical cleaning of the ossicle surface to eliminate residual disease. and L. Školoudík, E. Šimáková, D. Kalfeřt, V. Chrobok

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Relation:

Acta medica (Hradec Králové) Universitas Carolina, Facultas Medica Hradec Králové--MED00010947

Source:

Acta medica (Hradec Králové) | 2015 Volume:58 | Number:4

Harvested from:

CDK

Metadata only:

false

Date:

2015