Efficacy of topiramate as add-on therapy in two different types of progressive myoclonic epilepsy
Title:
Efficacy of topiramate as add-on therapy in two different types of progressive myoclonic epilepsy Efficacy of topiramate as add-on therapy in two different types of progressive myoclonic epilepsy
The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora's disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with marked decrease in myoclonic seizure frequency and improvement of quality of life. Topiramate appears to be a useful alternative agent in cases of PME and could be consider for adjunctive therapy. and CF. Demir, HH. Ozdemir, B. Müngen