Emerging role of interleukin-1 in cardiovascular diseases

Title:

Emerging role of interleukin-1 in cardiovascular diseases

Creator:

Vicenová, B., Václav Vopálenský, Burýšek, L., and Martin Pospíšek

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:aec4f927-a125-4030-a9f6-f0bde05dcffc
uuid:aec4f927-a125-4030-a9f6-f0bde05dcffc

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, cytokiny, kardiovaskulární nemoci, physiology, cytokines, cardiovascular diseases, interleukin-1, interleukin-1 receptor antagonist protein, signaling pathways, 14, and 612

Type:

article, články, model:article, and TEXT

Description:

There is an increasing eviden ce linking dysbalance between various proinflammatory mediators and higher risk of cardiovascular events and pathologies. Likewise, some of the cardiovascular diseases lately ap peared to have an autoimmune component. Interleukin-1 (IL-1), a master regulator of diverse inflammatory processes in higher eukaryotes and the key player in numerous autoimmune disorders including rheumatoid arthritis, diabetes mellitus or systemic sclerosis, has recently been proved to be involved in development of several cardiovascular diseases as well. This report aims to give a summary on current knowledge about the IL-1 signaling pathways and about the implication of IL-1 and the IL-1 receptor antagonist (IL-1Ra) in some of the diseases of the cardiovascular system., B. Vicenová ... [et al.]., and Obsahuje seznam literatury

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2009 Volume:58 | Number:4

Harvested from:

CDK

Metadata only:

false