Prenatal exposure to bisphenols and parabens and impacts on human physiology

Title:

Prenatal exposure to bisphenols and parabens and impacts on human physiology

Creator:

Lucie Kolátorová Sosvorová, Michaela Dušková, Jana Vítků, and Luboslav Stárka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:a2bd3351-a443-41f5-bc2c-83cbdc2028d1
uuid:a2bd3351-a443-41f5-bc2c-83cbdc2028d1
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, těhotenství, pregnancy, fetus, endocrine disruptor, bisphenol, paraben, 14, and 612

Type:

article, články, journal articles, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

In modern societies, living organisms are exposed daily to multiform pollution from industrial chemical products. Some of these substances have been shown to affect the endocrine system, and have been termed endocrine disruptors (EDs). Bisphenol A (BPA), which can leach from plastics, and parabens, used in cosmetic products, are among the most well-studied. Prenatal development is a vulnerable phase of human life, and disruptions during this period may have lifelong consequences. Since EDs are known to cross the placental barrier and BPA may accumulate in the fetus, "BPA-free" products have been introduced to the market. However, such products often contain alternative bisphenols (e.g. BPS, BPF) that have not yet been extensively examined or regulated. Moreover, alternative bisphenols often occur together with BPA. The human organism is thus exposed to a mixture of EDs, some of which can have additive or synergic effects. Recent findings have also shown that paraben exposure can alter bisphenol pharmacokinetics. Taking into account the widespread occurrence of various EDs and the potential multiplicity of their effects, doses of EDs currently considered safe may not actually be as safe as they appear, especially during pregnancy., L. Kolatorova, M. Duskova, J. Vitku, L. Starka., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2017 Volume:66 | Number:Suppl 3

Harvested from:

CDK

Metadata only:

false