Adiponectin and Its Role in the Obesity-Induced Insulin Resistance and Related Complications

Title:

Adiponectin and Its Role in the Obesity-Induced Insulin Resistance and Related Complications

Creator:

Haluzík, M., Pařízková, J., and Haluzík, M.M.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:79a28bf1-8d05-47f8-b94a-8c0ed86bee59
uuid:79a28bf1-8d05-47f8-b94a-8c0ed86bee59

Subject:

dipose tissue, Adiponectin, Leptin, Insulin resistance, Atherosclerosis, and Obesity

Type:

article, model:article, and TEXT

Description:

It is now generally accepted that adipose tissue acts as an endocrine organ producing a number of substances with an important role in the regulation of food intake, energy expenditure and a series of metabolic processes. Adiponectin is a recently discovered protein produced exclusively by adipocytes. A number of studies have shown that obesity, insulin resistance and atherosclerosis are accompanied by decreased adiponectin levels and that adiponectin replacement under experimental settings is able to diminish both insulin resistance and atherosclerosis. The aim of this review is to summarize the current knowledge about the physiology and pathophysiology of adiponectin and to discuss its potential in the treatment of insulin resistance and atherosclerosis.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2004 Volume:53 | Number:2

Harvested from:

CDK

Metadata only:

false